HitPredict

Interactor 1: PSB8 (P28062)
Proteasome subunit beta type-8 (EC 3.4.25.1) (Low molecular mass protein 7) (Macropain subunit C13) (Multicatalytic endopeptidase complex subunit C13) (Proteasome component C13) (Proteasome subunit beta-5i) (Really interesting new gene 10 protein)
Gene: PSMB8

Interactor 2: POMP (Q9Y244)
Proteasome maturation protein (Proteassemblin) (Protein UMP1 homolog) (hUMP1) (Voltage-gated K channel beta subunit 4.1)
Gene: POMP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	1.00	0.868

Property	Details
Experiments	33961781, 15944226, 17948026
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Proteasome~UMP1
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 276 Hs			1 141
+	Hs
		1152327 Q6IBT1_HUMAN (70-264): 1.04e-83: 254: 26.15		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		1303498 PSB7_HUMAN (70-264): 7.13e-84: 254: 26.15		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		656796 PSB5_HUMAN (1-272): 5.65e-83: 251: 58.09		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		656342 PSA5_HUMAN (49-271): 1.86e-82: 249: 16.81		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		637759 PSA2_HUMAN (49-272): 1.11e-79: 242: 19.31		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		638220 PSA4_HUMAN (47-268): 1.58e-79: 242: 16.88		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		656662 PSB6_HUMAN (52-255): 8.9e-80: 242: 31.22		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		893773 PSA6_HUMAN (43-275): 8.03e-80: 242: 13.31		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		771482 PSB10_HUMAN (37-261): 8.91e-75: 231: 27.07		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Dm
		1367991 Q9VUJ1_DROME (75-266): 1.76e-85: 258: 26.56		Q9VIJ5_DROME (40-140): 1.87e-46: 148: 50.50
+	Dm
		1178961 Q7K148_DROME (1-274): 2.23e-84: 255: 49.10		Q9VIJ5_DROME (40-140): 1.87e-46: 148: 50.50
+	Dm
		1367996 Q9W470_DROME (69-266): 3.8e-83: 253: 25.25		Q9VIJ5_DROME (40-140): 1.87e-46: 148: 50.50
+	Dm
		1278643 PSA5_DROME (49-272): 1.59e-81: 247: 18.67		Q9VIJ5_DROME (40-140): 1.87e-46: 148: 50.50
+	Hs
		656143 PSB9_HUMAN (68-255): 2.77e-22: 93.6: 33.51		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Dm
		47622 A0AQH0_DROME (69-255): 5.33e-19: 85.1: 29.79		Q9VIJ5_DROME (40-140): 1.87e-46: 148: 50.50