HitPredict

Interactor 1: PSA5 (P28066)
Proteasome subunit alpha type-5 (Macropain zeta chain) (Multicatalytic endopeptidase complex zeta chain) (Proteasome zeta chain)
Gene: PSMA5

Interactor 2: PSMG2 (Q969U7)
Proteasome assembly chaperone 2 (PAC-2) (Hepatocellular carcinoma-susceptibility protein 3) (Tumor necrosis factor superfamily member 5-induced protein 1)
Gene: PSMG2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	33961781, 26186194, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PAC2~Proteasome_A_N
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 241 Hs			1 264
+	Hs
		637728 PSA2_HUMAN (3-241): 3.37e-89: 265: 30.96		PSMG2_HUMAN (1-264): 8.69e-146: 410: 100.00
+	Hs
		156335 PSA7_HUMAN (8-239): 7.45e-89: 264: 36.17		PSMG2_HUMAN (1-264): 8.69e-146: 410: 100.00
+	Hs
		637506 PSA1_HUMAN (3-241): 1.03e-88: 264: 28.81		PSMG2_HUMAN (1-264): 8.69e-146: 410: 100.00
+	Hs
		893724 PSA6_HUMAN (4-241): 1.93e-88: 263: 25.93		PSMG2_HUMAN (1-264): 8.69e-146: 410: 100.00
+	Dm
		1278642 PSA5_DROME (1-241): 1.3e-103: 301: 70.37		Q9VEC2_DROME (1-264): 7.68e-111: 321: 25.09
+	Dm
		771313 PSA2_DROME (3-241): 1.55e-99: 291: 31.38		Q9VEC2_DROME (1-264): 7.68e-111: 321: 25.09
+	Hs
		1250770 PSMA8_HUMAN (6-235): 3.19e-44: 150: 37.24		PSMG2_HUMAN (1-264): 8.69e-146: 410: 100.00