HitPredict

Interactor 1: PSA5 (P28066)
Proteasome subunit alpha type-5 (Macropain zeta chain) (Multicatalytic endopeptidase complex zeta chain) (Proteasome zeta chain)
Gene: PSMA5

Interactor 2: POMP (Q9Y244)
Proteasome maturation protein (Proteassemblin) (Protein UMP1 homolog) (hUMP1) (Voltage-gated K channel beta subunit 4.1)
Gene: POMP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	33961781, 35271311, 17189198
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Proteasome~UMP1
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 241 Hs			1 141
+	Hs
		637759 PSA2_HUMAN (3-241): 3.37e-89: 265: 30.96		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		156378 PSA7_HUMAN (8-239): 7.45e-89: 264: 36.17		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		637608 PSA1_HUMAN (3-241): 1.03e-88: 264: 28.81		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		893773 PSA6_HUMAN (4-241): 1.93e-88: 263: 25.93		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Dm
		1278643 PSA5_DROME (1-241): 1.3e-103: 301: 70.37		Q9VIJ5_DROME (40-140): 1.87e-46: 148: 50.50
+	Dm
		771316 PSA2_DROME (3-241): 1.55e-99: 291: 31.38		Q9VIJ5_DROME (40-140): 1.87e-46: 148: 50.50