HitPredict

Interactor 1: PSB4 (P28070)
Proteasome subunit beta type-4 (26 kDa prosomal protein) (HsBPROS26) (PROS-26) (Macropain beta chain) (Multicatalytic endopeptidase complex beta chain) (Proteasome beta chain) (Proteasome chain 3) (HsN3)
Gene: PSMB4

Interactor 2: RD23B (P54727)
UV excision repair protein RAD23 homolog B (HR23B) (hHR23B) (XP-C repair-complementing complex 58 kDa protein) (p58)
Gene: RAD23B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27114451
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 264 Hs			1 409
+	Hs
		656184 PSA5_HUMAN (26-252): 6.98e-77: 234: 13.69		RD23B_HUMAN (1-409): 1.31e-125: 370: 100.00
+	Hs
		156261 PSA7_HUMAN (33-255): 6.14e-76: 232: 14.16		RD23B_HUMAN (1-409): 1.31e-125: 370: 100.00
+	Hs
		656435 PSB4_HUMAN (1-264): 6.75e-82: 248: 100.00		RD23A_HUMAN (1-409): 9.12e-94: 287: 56.72
+	Hs
		656183 PSA5_HUMAN (26-252): 6.98e-77: 234: 13.69		RD23A_HUMAN (1-409): 9.12e-94: 287: 56.72
+	Hs
		156260 PSA7_HUMAN (33-255): 6.14e-76: 232: 14.16		RD23A_HUMAN (1-409): 9.12e-94: 287: 56.72
+	Sc
		675403 PSB5_YEAST (17-264): 4.06e-81: 247: 23.44		RAD23_YEAST (1-407): 2.12e-72: 233: 28.41
+	Hs
		656545 PSB4_HUMAN (1-264): 6.75e-82: 248: 100.00		UBQL1_HUMAN (1-404): 1.25e-57: 200: 13.72
+	Hs
		656337 PSA5_HUMAN (26-252): 6.98e-77: 234: 13.69		UBQL1_HUMAN (1-404): 1.25e-57: 200: 13.72
+	Hs
		156375 PSA7_HUMAN (33-255): 6.14e-76: 232: 14.16		UBQL1_HUMAN (1-404): 1.25e-57: 200: 13.72
+	Hs
		656539 PSB4_HUMAN (1-264): 6.75e-82: 248: 100.00		UBQL2_HUMAN (1-364): 5.93e-51: 182: 13.68
+	Hs
		656327 PSA5_HUMAN (26-252): 6.98e-77: 234: 13.69		UBQL2_HUMAN (1-364): 5.93e-51: 182: 13.68
+	Hs
		156369 PSA7_HUMAN (33-255): 6.14e-76: 232: 14.16		UBQL2_HUMAN (1-364): 5.93e-51: 182: 13.68
+	Hs
		656323 PSA5_HUMAN (26-252): 6.98e-77: 234: 13.69		UBQL4_HUMAN (1-364): 2.75e-45: 166: 12.71
+	Hs
		156361 PSA7_HUMAN (33-255): 6.14e-76: 232: 14.16		UBQL4_HUMAN (1-364): 2.75e-45: 166: 12.71
+	Dm
		1371323 PSB4_DROME (11-263): 3.53e-75: 231: 39.54		Q9VWD9_DROME (1-353): 1.07e-44: 164: 11.08
+	Dm
		1278653 PSA5_DROME (26-255): 4.47e-75: 230: 14.23		Q9VWD9_DROME (1-353): 1.07e-44: 164: 11.08
+	Hs
		656197 PSA5_HUMAN (26-252): 6.98e-77: 234: 13.69		RL40_HUMAN (1-91): 3.57e-33: 122: 28.57
+	At
		188696 PSA2A_ARATH (28-258): 1.1e-77: 236: 15.00		UBQ3_ARATH (1-80): 7.66e-29: 116: 28.75
+	At
		1091773 PSA2B_ARATH (28-258): 6.13e-77: 234: 15.00		UBQ3_ARATH (1-80): 7.66e-29: 116: 28.75
+	At
		286449 PSA6A_ARATH (26-261): 3.47e-75: 230: 13.71		UBQ3_ARATH (1-80): 7.66e-29: 116: 28.75