HitPredict

Interactor 1: PSB4 (P28070)
Proteasome subunit beta type-4 (26 kDa prosomal protein) (HsBPROS26) (PROS-26) (Macropain beta chain) (Multicatalytic endopeptidase complex beta chain) (Proteasome beta chain) (Proteasome chain 3) (HsN3)
Gene: PSMB4

Interactor 2: DDI2 (Q5TDH0)
Protein DDI1 homolog 2 (EC 3.4.23.-)
Gene: DDI2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27114451
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 264 Hs			1 399
+	Hs
		656249 PSA5_HUMAN (26-252): 6.98e-77: 234: 13.69		DDI2_HUMAN (1-399): 1.67e-162: 463: 100.00
+	Hs
		156308 PSA7_HUMAN (33-255): 6.14e-76: 232: 14.16		DDI2_HUMAN (1-399): 1.67e-162: 463: 100.00
+	Hs
		656507 PSB4_HUMAN (1-264): 6.75e-82: 248: 100.00		DDI1_HUMAN (1-392): 7.44e-148: 426: 70.75
+	Hs
		656280 PSA5_HUMAN (26-252): 6.98e-77: 234: 13.69		DDI1_HUMAN (1-392): 7.44e-148: 426: 70.75
+	Hs
		156329 PSA7_HUMAN (33-255): 6.14e-76: 232: 14.16		DDI1_HUMAN (1-392): 7.44e-148: 426: 70.75
+	Hs
		656545 PSB4_HUMAN (1-264): 6.75e-82: 248: 100.00		UBQL1_HUMAN (5-241): 5.78e-49: 176: 14.80
+	Hs
		656539 PSB4_HUMAN (1-264): 6.75e-82: 248: 100.00		UBQL2_HUMAN (5-241): 1.08e-47: 173: 15.20
+	Hs
		656337 PSA5_HUMAN (26-252): 6.98e-77: 234: 13.69		UBQL1_HUMAN (5-241): 5.78e-49: 176: 14.80
+	Hs
		156375 PSA7_HUMAN (33-255): 6.14e-76: 232: 14.16		UBQL1_HUMAN (5-241): 5.78e-49: 176: 14.80
+	Hs
		656327 PSA5_HUMAN (26-252): 6.98e-77: 234: 13.69		UBQL2_HUMAN (5-241): 1.08e-47: 173: 15.20
+	Hs
		156369 PSA7_HUMAN (33-255): 6.14e-76: 232: 14.16		UBQL2_HUMAN (5-241): 1.08e-47: 173: 15.20
+	Hs
		656323 PSA5_HUMAN (26-252): 6.98e-77: 234: 13.69		UBQL4_HUMAN (8-241): 1.8e-44: 164: 14.59
+	Hs
		156361 PSA7_HUMAN (33-255): 6.14e-76: 232: 14.16		UBQL4_HUMAN (8-241): 1.8e-44: 164: 14.59
+	Dm
		1371323 PSB4_DROME (11-263): 3.53e-75: 231: 39.54		Q9VWD9_DROME (5-241): 8.99e-44: 161: 16.39
+	Dm
		1278653 PSA5_DROME (26-255): 4.47e-75: 230: 14.23		Q9VWD9_DROME (5-241): 8.99e-44: 161: 16.39
+	Dm
		1178971 Q7K148_DROME (50-242): 4.09e-74: 229: 25.91		Q9VWD9_DROME (5-241): 8.99e-44: 161: 16.39
+	Hs
		656435 PSB4_HUMAN (1-264): 6.75e-82: 248: 100.00		RD23A_HUMAN (3-198): 2.36e-28: 116: 15.00
+	Sc
		675403 PSB5_YEAST (17-264): 4.06e-81: 247: 23.44		RAD23_YEAST (5-202): 3.88e-26: 110: 16.00
+	Hs
		656183 PSA5_HUMAN (26-252): 6.98e-77: 234: 13.69		RD23A_HUMAN (3-198): 2.36e-28: 116: 15.00
+	Hs
		156260 PSA7_HUMAN (33-255): 6.14e-76: 232: 14.16		RD23A_HUMAN (3-198): 2.36e-28: 116: 15.00