HitPredict

Interactor 1: PSB5 (P28074)
Proteasome subunit beta type-5 (EC 3.4.25.1) (Macropain epsilon chain) (Multicatalytic endopeptidase complex epsilon chain) (Proteasome chain 6) (Proteasome epsilon chain) (Proteasome subunit MB1) (Proteasome subunit X)
Gene: PSMB5

Interactor 2: POMP (Q9Y244)
Proteasome maturation protein (Proteassemblin) (Protein UMP1 homolog) (hUMP1) (Voltage-gated K channel beta subunit 4.1)
Gene: POMP

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	1.00	0.949

Property	Details
Experiments	35271311, 14733938, 20980621, 15944226, 17948026, 17189198
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Proteasome~UMP1
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 263 Hs			1 141
+	Hs
		656085 PSB8_HUMAN (1-261): 7.16e-89: 266: 57.46		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		656342 PSA5_HUMAN (28-258): 1.29e-86: 259: 15.64		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		1303498 PSB7_HUMAN (39-251): 2.76e-83: 252: 25.82		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		637759 PSA2_HUMAN (30-259): 6.04e-80: 242: 18.64		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		638220 PSA4_HUMAN (32-255): 1.03e-79: 242: 18.22		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		771482 PSB10_HUMAN (44-248): 1.91e-78: 239: 27.32		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		656662 PSB6_HUMAN (43-245): 4.34e-77: 235: 31.37		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		1152327 Q6IBT1_HUMAN (1-251): 2.01e-72: 224: 25.10		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Dm
		1178961 Q7K148_DROME (1-260): 9.47e-85: 256: 51.46		Q9VIJ5_DROME (40-140): 1.87e-46: 148: 50.50
+	Dm
		1367991 Q9VUJ1_DROME (62-253): 1.16e-84: 255: 27.08		Q9VIJ5_DROME (40-140): 1.87e-46: 148: 50.50
+	Dm
		1278643 PSA5_DROME (28-259): 3.23e-84: 253: 16.67		Q9VIJ5_DROME (40-140): 1.87e-46: 148: 50.50
+	Dm
		1367996 Q9W470_DROME (51-253): 2.14e-74: 230: 27.09		Q9VIJ5_DROME (40-140): 1.87e-46: 148: 50.50
+	Dm
		47622 A0AQH0_DROME (42-245): 2.57e-71: 220: 27.81		Q9VIJ5_DROME (40-140): 1.87e-46: 148: 50.50
+	Hs
		656143 PSB9_HUMAN (55-242): 2.58e-18: 82.8: 30.16		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00