HitPredict

Interactor 1: UBC8 (P28263)
Ubiquitin-conjugating enzyme E2-24 kDa (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 8) (Glucose-induced degradation protein 3) (Ubiquitin carrier protein) (Ubiquitin-protein ligase)
Gene: UBC8

Interactor 2: HSP7F (P32589)
Heat shock protein homolog SSE1 (Chaperone protein MSI3)
Gene: SSE1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	19536198
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 218 Sc			1 693
+	Hs
		504528 UB2E3_HUMAN (1-148): 4.38e-69: 211: 29.14		HSP7C_HUMAN (2-645): 0: 851: 27.04
+	Hs
		503677 UB2R1_HUMAN (3-212): 3.83e-63: 197: 19.38		HSP7C_HUMAN (2-645): 0: 851: 27.04
+	Hs
		564035 UB2R1_HUMAN (3-212): 3.83e-63: 197: 19.38		HSP76_HUMAN (4-643): 0: 842: 26.28
+	Hs
		827884 UB2R1_HUMAN (3-212): 3.83e-63: 197: 19.38		HSP72_HUMAN (2-644): 0: 840: 27.08
+	Hs
		503827 UBE2H_HUMAN (2-154): 4.9e-58: 182: 58.82		HSP7C_HUMAN (2-645): 0: 851: 27.04
+	Hs
		828965 UBE2A_HUMAN (37-145): 1.11e-25: 99.4: 42.20		HSP72_HUMAN (2-644): 0: 840: 27.08
+	Hs
		714137 UB2R1_HUMAN (3-212): 3.83e-63: 197: 19.38		HSP74_HUMAN (6-650): 5.45e-136: 421: 38.47
+	Hs
		320829 UB2R1_HUMAN (3-212): 3.83e-63: 197: 19.38		HS74L_HUMAN (6-650): 1.32e-134: 418: 35.85
+	Hs
		714170 UBE2H_HUMAN (2-154): 4.9e-58: 182: 58.82		HSP74_HUMAN (6-650): 5.45e-136: 421: 38.47
+	Hs
		320840 UBE2H_HUMAN (2-154): 4.9e-58: 182: 58.82		HS74L_HUMAN (6-650): 1.32e-134: 418: 35.85
+	Hs
		908899 UBE2H_HUMAN (2-154): 4.9e-58: 182: 58.82		HS105_HUMAN (6-687): 1.23e-133: 416: 36.05
+	Sc
		493108 UBC4_YEAST (1-148): 6.06e-74: 222: 35.10		HSP72_YEAST (1-382): 1.15e-71: 246: 36.82
+	Sc
		490533 UBC8_YEAST (1-218): 3.13e-68: 210: 100.00		HSP71_YEAST (1-382): 7.01e-71: 244: 36.55
+	Sc
		494450 UBC13_YEAST (1-151): 7.72e-65: 199: 33.77		HSP72_YEAST (1-382): 1.15e-71: 246: 36.82
+	Sc
		491836 UBC13_YEAST (1-151): 7.72e-65: 199: 33.77		HSP71_YEAST (1-382): 7.01e-71: 244: 36.55
+	Sc
		410205 UBC2_YEAST (27-145): 1.59e-24: 96.7: 40.34		HSP72_YEAST (1-382): 1.15e-71: 246: 36.82
+	Sc
		410204 UBC2_YEAST (27-145): 1.59e-24: 96.7: 40.34		HSP71_YEAST (1-382): 7.01e-71: 244: 36.55