Interactor 1: ABCD3 (P28288)
ATP-binding cassette sub-family D member 3 (EC 3.1.2.-) (EC 7.6.2.-) (70 kDa peroxisomal membrane protein) (PMP70)
Gene: ABCD3

Interactor 2: ABCD1 (P33897)
ATP-binding cassette sub-family D member 1 (EC 3.1.2.-) (EC 7.6.2.-) (Adrenoleukodystrophy protein) (ALDP)
Gene: ABCD1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.50 1.00 0.713

The method score is based on:

Property Details
Experiments 10551832
Identification Methods two hybrid, coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ABC_membrane_2~ABC_membrane_2, ABC_membrane_2~ABC_tran, ABC_tran~ABC_tran
Common GO terms GO:0000038 - very long-chain fatty acid metabolic process
GO:0005324 - long-chain fatty acid transmembrane transporter activity
GO:0005524 - ATP binding
GO:0005777 - peroxisome
GO:0005778 - peroxisomal membrane
and 10 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 659
Hs

1 745
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Sc
+ Sc
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Mt
+ Ce

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Last updated: 15 Jul 2024