HitPredict

Interactor 1: TMOD1 (P28289)
Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod)
Gene: TMOD1

Interactor 2: ACTA (P62736)
Actin, aortic smooth muscle (EC 3.6.4.-) (Alpha-actin-2) (Cell growth-inhibiting gene 46 protein) [Cleaved into: Actin, aortic smooth muscle, intermediate form]
Gene: ACTA2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	37071682
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~Tropomodulin
Common GO terms	GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 359 Hs			1 377
+	Hs
		1122520 TMOD3_HUMAN (1-345): 6.33e-150: 428: 62.14		ACTBL_HUMAN (4-377): 0: 712: 87.97
+	Hs
		657477 TMOD1_HUMAN (1-359): 2.27e-161: 457: 100.00		ACTB_HUMAN (4-377): 0: 598: 94.12
+	Hs
		657481 TMOD1_HUMAN (1-359): 2.27e-161: 457: 100.00		ACTG_HUMAN (4-377): 0: 598: 94.39
+	Hs
		892073 TMOD3_HUMAN (1-345): 6.33e-150: 428: 62.14		ACTB_HUMAN (4-377): 0: 598: 94.12
+	Hs
		932411 TMOD3_HUMAN (1-345): 6.33e-150: 428: 62.14		ACTC_HUMAN (1-377): 0: 598: 98.41
+	Hs
		915520 TMOD3_HUMAN (1-345): 6.33e-150: 428: 62.14		ACTA_HUMAN (1-377): 0: 596: 100.00
+	Hs
		892077 TMOD2_HUMAN (1-345): 1.55e-144: 414: 59.25		ACTB_HUMAN (4-377): 0: 598: 94.12
+	Hs
		930031 TMOD2_HUMAN (1-345): 1.55e-144: 414: 59.25		ACTG_HUMAN (4-377): 0: 598: 94.39
+	Hs
		932417 TMOD2_HUMAN (1-345): 1.55e-144: 414: 59.25		ACTC_HUMAN (1-377): 0: 598: 98.41
+	Hs
		886390 NAL12_HUMAN (185-323): 4.52e-17: 84.8: 19.86		ACTB_HUMAN (4-377): 0: 598: 94.12
+	Hs
		932227 NLRC3_HUMAN (186-351): 8.99e-17: 84: 19.41		ACTC_HUMAN (1-377): 0: 598: 98.41