HitPredict

Interactor 1: TMOD1 (P28289)
Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod)
Gene: TMOD1

Interactor 2: CALD1 (Q05682)
Caldesmon (CDM)
Gene: CALD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005523 - tropomyosin binding GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0006936 - muscle contraction and 1 others more... GO:0030016 - myofibril
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 359 Hs			1 793
+	Hs
		984668 TMOD3_HUMAN (1-345): 6.33e-150: 428: 62.14		CALD1_HUMAN (1-793): 4.35e-43: 169: 100.00
+	Hs
		657530 TMOD1_HUMAN (1-359): 2.27e-161: 457: 100.00		MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98
+	Hs
		657463 TMOD1_HUMAN (1-359): 2.27e-161: 457: 100.00		MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87
+	Hs
		1268101 TMOD3_HUMAN (1-345): 6.33e-150: 428: 62.14		MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98
+	Hs
		657496 TMOD1_HUMAN (1-359): 2.27e-161: 457: 100.00		GOGB1_HUMAN (5-752): 1.76e-17: 89.9: 10.43
+	Hs
		1348581 TMOD3_HUMAN (1-345): 6.33e-150: 428: 62.14		MYO5A_HUMAN (42-632): 2.15e-24: 112: 15.29
+	Hs
		725044 TMOD3_HUMAN (1-345): 6.33e-150: 428: 62.14		MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87
+	Hs
		1349403 TMOD4_HUMAN (2-343): 3.86e-142: 408: 58.77		MYO5A_HUMAN (42-632): 2.15e-24: 112: 15.29
+	Hs
		657551 TMOD1_HUMAN (1-359): 2.27e-161: 457: 100.00		MYO5C_HUMAN (13-485): 5.4e-09: 62.2: 14.38
+	Hs
		149373 TMOD2_HUMAN (1-345): 1.55e-144: 414: 59.25		CTRO_HUMAN (122-718): 1.01e-14: 81: 9.87
+	Hs
		1343904 TMOD3_HUMAN (1-345): 6.33e-150: 428: 62.14		MYO5C_HUMAN (13-485): 5.4e-09: 62.2: 14.38
+	Hs
		1343906 TMOD4_HUMAN (2-343): 3.86e-142: 408: 58.77		MYO5C_HUMAN (13-485): 5.4e-09: 62.2: 14.38
+	Hs
		668146 LMOD1_HUMAN (3-120): 2.46e-14: 75.9: 33.90		CALD1_HUMAN (1-793): 4.35e-43: 169: 100.00
+	Hs
		1059274 NOD2_HUMAN (143-346): 9.86e-15: 77.4: 15.53		GOGB1_HUMAN (5-752): 1.76e-17: 89.9: 10.43
+	Hs
		81638 NOD2_HUMAN (143-346): 9.86e-15: 77.4: 15.53		B7Z6G4_HUMAN (3-434): 5.77e-12: 71: 51.62