HitPredict

Interactor 1: YJU2 (P28320)
Splicing factor YJU2
Gene: YJU2

Interactor 2: SYF1 (Q04048)
Pre-mRNA-splicing factor SYF1 (PRP19-associated complex protein 90) (Synthetic lethal with CDC40 protein 1)
Gene: SYF1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.749

Property	Details
Experiments	10688190, 11805826, 28919079, 17515604, 23438600, 19617314, 37968396, 16429126
Identification Methods	two hybrid, tandem affinity purification, affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000349 - generation of catalytic spliceosome for first transesterification step GO:0005634 - nucleus GO:0071006 - U2-type catalytic step 1 spliceosome GO:0071007 - U2-type catalytic step 2 spliceosome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 278 Sc			1 859
+	Hs
		534271 YJU2B_HUMAN (1-214): 4.04e-78: 243: 25.66		SYF1_HUMAN (30-845): 1.94e-154: 476: 21.48
+	Hs
		1314503 YJU2_HUMAN (1-207): 9.34e-65: 207: 33.33		SYF1_HUMAN (30-845): 1.94e-154: 476: 21.48
+	Sc
		657779 YJU2_YEAST (1-278): 2.33e-115: 334: 100.00		CLF1_YEAST (4-377): 2.18e-12: 72.7: 11.71
+	Hs
		534268 YJU2B_HUMAN (1-214): 4.04e-78: 243: 25.66		CRNL1_HUMAN (8-269): 3.6e-11: 69.3: 18.80
+	Hs
		1314499 YJU2_HUMAN (1-207): 9.34e-65: 207: 33.33		CRNL1_HUMAN (8-269): 3.6e-11: 69.3: 18.80