HitPredict

Interactor 1: ELK4 (P28324)
ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1) (SRF accessory protein 1)
Gene: ELK4

Interactor 2: MK08 (P45983)
Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (JNK-46) (Stress-activated protein kinase 1c) (SAPK1c) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)
Gene: MAPK8

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.53	0.60	0.569

Property	Details
Experiments	9020136
Identification Methods	enzymatic study, in-gel kinase assay
Interaction Type	direct interaction, phosphorylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 431 Hs			1 427
+	Hs
		584217 ELK1_HUMAN (1-430): 3.04e-36: 139: 31.17		MK08_HUMAN (1-427): 6.2e-164: 469: 100.00
+	Hs
		584226 ELK1_HUMAN (1-430): 3.04e-36: 139: 31.17		MK10_HUMAN (1-427): 6.5e-163: 468: 90.16
+	Hs
		584218 ELK1_HUMAN (1-430): 3.04e-36: 139: 31.17		MK09_HUMAN (1-427): 5.18e-163: 467: 80.80
+	Hs
		800726 ETV1_HUMAN (3-147): 3.97e-28: 117: 38.62		MK08_HUMAN (1-427): 6.2e-164: 469: 100.00
+	Hs
		542010 ETS1_HUMAN (3-108): 2.13e-41: 154: 45.79		MK07_HUMAN (16-403): 1.72e-133: 404: 38.06
+	Hs
		840374 ERF_HUMAN (4-371): 2.84e-46: 169: 23.56		MK14_HUMAN (4-365): 2.33e-130: 381: 46.03
+	Hs
		542017 ETS1_HUMAN (3-108): 2.13e-41: 154: 45.79		MK14_HUMAN (4-365): 2.33e-130: 381: 46.03
+	Hs
		657805 ELK4_HUMAN (1-431): 6.02e-55: 189: 100.00		MK01_HUMAN (20-359): 2.94e-84: 263: 42.98
+	Hs
		647473 ELK4_HUMAN (1-431): 6.02e-55: 189: 100.00		MK03_HUMAN (20-359): 5.22e-83: 261: 41.26
+	Hs
		658856 ERF_HUMAN (4-371): 2.84e-46: 169: 23.56		MK01_HUMAN (20-359): 2.94e-84: 263: 42.98
+	Rn
		88640 D3ZJW0_RAT (4-371): 2.93e-46: 169: 23.56		MK03_RAT (20-359): 1.42e-83: 262: 41.55
+	Hs
		647519 ERF_HUMAN (4-371): 2.84e-46: 169: 23.56		MK03_HUMAN (20-359): 5.22e-83: 261: 41.26
+	Hs
		541984 ETS1_HUMAN (3-108): 2.13e-41: 154: 45.79		MK01_HUMAN (20-359): 2.94e-84: 263: 42.98
+	Rn
		78170 B5DEX5_RAT (4-107): 1.26e-44: 154: 47.62		MK03_RAT (20-359): 1.42e-83: 262: 41.55
+	Mm
		785336 ELK1_MOUSE (1-430): 9.58e-39: 146: 30.72		MK01_MOUSE (20-359): 2.95e-84: 263: 42.98
+	Mm
		785338 ELK1_MOUSE (1-430): 9.58e-39: 146: 30.72		MK03_MOUSE (20-370): 9.11e-84: 263: 40.56
+	Hs
		584208 ELK1_HUMAN (1-430): 3.04e-36: 139: 31.17		MK01_HUMAN (20-359): 2.94e-84: 263: 42.98
+	Hs
		584206 ELK1_HUMAN (1-430): 3.04e-36: 139: 31.17		MK03_HUMAN (20-359): 5.22e-83: 261: 41.26
+	Hs
		658826 ETV3_HUMAN (4-410): 2.26e-31: 127: 21.08		MK01_HUMAN (20-359): 2.94e-84: 263: 42.98
+	Hs
		647520 ETV1_HUMAN (3-147): 3.97e-28: 117: 38.62		MK03_HUMAN (20-359): 5.22e-83: 261: 41.26