HitPredict

Interactor 1: 5HT2C (P28335)
5-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) (5-HT1C) (Serotonin receptor 2C)
Gene: HTR2C

Interactor 2: 5HT2C (P28335)
5-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) (5-HT1C) (Serotonin receptor 2C)
Gene: HTR2C

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.827

The method score is based on:

Property Details
Experiments 28258217, 15518545, 16195233
Identification Methods anti tag coimmunoprecipitation, cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains 7tm_1~7tm_1
Common GO terms GO:0001587 - Gq/11-coupled serotonin receptor activity
GO:0001662 - behavioral fear response
GO:0004993 - G protein-coupled serotonin receptor activity
GO:0005886 - plasma membrane
GO:0006874 - intracellular calcium ion homeostasis
and 22 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 458
Hs

1 458
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024