HitPredict

Interactor 1: 5HT2C (P28335)
5-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) (5-HT1C) (Serotonin receptor 2C)
Gene: HTR2C

Interactor 2: APBA1 (Q02410)
Amyloid-beta A4 precursor protein-binding family A member 1 (Adapter protein X11alpha) (Neuron-specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint-1)
Gene: APBA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	12006486
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0007268 - chemical synaptic transmission GO:0007626 - locomotory behavior
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 458 Hs			1 837
+	Hs
		658221 5HT2C_HUMAN (1-458): 1.97e-103: 317: 100.00		DLG4_HUMAN (358-759): 3.74e-28: 123: 13.43
+	Hs
		658227 5HT2C_HUMAN (1-458): 1.97e-103: 317: 100.00		DLG1_HUMAN (519-758): 2.64e-24: 111: 16.25
+	Hs
		658236 5HT2C_HUMAN (1-458): 1.97e-103: 317: 100.00		SCRIB_HUMAN (642-817): 3.96e-20: 98.4: 18.46
+	Rn
		223210 5HT2C_RAT (1-458): 1.11e-107: 328: 88.04		MPDZ_RAT (329-755): 4.66e-16: 85.3: 11.87
+	Hs
		280022 5HT2C_HUMAN (1-458): 1.97e-103: 317: 100.00		MPDZ_HUMAN (427-770): 3.39e-18: 92.2: 12.87
+	Hs
		656994 5HT2A_HUMAN (4-458): 5.97e-84: 267: 50.22		DLG4_HUMAN (358-759): 3.74e-28: 123: 13.43
+	Hs
		600726 DRD1_HUMAN (70-385): 2.99e-83: 265: 27.88		DLG4_HUMAN (358-759): 3.74e-28: 123: 13.43
+	Hs
		656997 5HT2A_HUMAN (4-458): 5.97e-84: 267: 50.22		DLG1_HUMAN (519-758): 2.64e-24: 111: 16.25
+	Mm
		830268 SSR4_MOUSE (23-389): 1.21e-68: 225: 20.57		DLG2_MOUSE (329-735): 1.13e-36: 150: 10.93
+	Rn
		495779 ADRB2_RAT (19-438): 1.92e-78: 251: 24.18		DLG4_RAT (358-759): 3.45e-28: 123: 13.43
+	Hs
		441650 ADRB1_HUMAN (13-409): 5.38e-77: 249: 25.62		DLG4_HUMAN (358-759): 3.74e-28: 123: 13.43
+	Hs
		626682 ADA1D_HUMAN (24-447): 1.69e-77: 253: 24.47		DLG1_HUMAN (519-758): 2.64e-24: 111: 16.25
+	Hs
		280021 5HT2A_HUMAN (4-458): 5.97e-84: 267: 50.22		MPDZ_HUMAN (427-770): 3.39e-18: 92.2: 12.87
+	Hs
		626687 ADA1D_HUMAN (24-447): 1.69e-77: 253: 24.47		SCRIB_HUMAN (642-817): 3.96e-20: 98.4: 18.46
+	Hs
		441654 ADRB1_HUMAN (13-409): 5.38e-77: 249: 25.62		MAGI2_HUMAN (111-754): 3.59e-20: 98.7: 10.69
+	Mm
		676818 SSR2_MOUSE (33-413): 7.81e-69: 225: 18.86		DLG4_MOUSE (358-759): 6.84e-28: 122: 13.19
+	Mm
		830267 SSR4_MOUSE (23-389): 1.21e-68: 225: 20.57		DLG4_MOUSE (358-759): 6.84e-28: 122: 13.19
+	Mm
		676812 SSR1_MOUSE (39-387): 1.05e-65: 217: 23.10		DLG4_MOUSE (358-759): 6.84e-28: 122: 13.19
+	Hs
		280029 5HT2B_HUMAN (27-401): 1.83e-70: 233: 44.96		MPDZ_HUMAN (427-770): 3.39e-18: 92.2: 12.87
+	Hs
		280028 DRD3_HUMAN (22-385): 4.42e-69: 226: 25.79		MPDZ_HUMAN (427-770): 3.39e-18: 92.2: 12.87