HitPredict

Interactor 1: 5HT2C (P28335)
5-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) (5-HT1C) (Serotonin receptor 2C)
Gene: HTR2C

Interactor 2: DLG1 (Q12959)
Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) (hDlg)
Gene: DLG1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	30126976
Identification Methods	p8 filamentous phage display
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0007268 - chemical synaptic transmission
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 458 Hs			1 904
+	Hs
		656997 5HT2A_HUMAN (4-458): 5.97e-84: 267: 50.22		DLG1_HUMAN (1-904): 0: 725: 100.00
+	Hs
		626682 ADA1D_HUMAN (24-447): 1.69e-77: 253: 24.47		DLG1_HUMAN (1-904): 0: 725: 100.00
+	Hs
		676802 SSR1_HUMAN (39-387): 2.15e-64: 214: 23.10		DLG1_HUMAN (1-904): 0: 725: 100.00
+	Hs
		658221 5HT2C_HUMAN (1-458): 1.97e-103: 317: 100.00		DLG4_HUMAN (86-493): 2.62e-24: 111: 15.64
+	Hs
		658236 5HT2C_HUMAN (1-458): 1.97e-103: 317: 100.00		SCRIB_HUMAN (217-396): 1.59e-23: 109: 41.49
+	Hs
		656994 5HT2A_HUMAN (4-458): 5.97e-84: 267: 50.22		DLG4_HUMAN (86-493): 2.62e-24: 111: 15.64
+	Hs
		159159 ADA1D_HUMAN (24-447): 1.69e-77: 253: 24.47		CSKP_HUMAN (19-360): 4.23e-28: 124: 10.64
+	Hs
		600726 DRD1_HUMAN (70-385): 2.99e-83: 265: 27.88		DLG4_HUMAN (86-493): 2.62e-24: 111: 15.64
+	Rn
		495779 ADRB2_RAT (19-438): 1.92e-78: 251: 24.18		DLG4_RAT (86-493): 2.93e-24: 111: 15.40
+	Hs
		626687 ADA1D_HUMAN (24-447): 1.69e-77: 253: 24.47		SCRIB_HUMAN (217-396): 1.59e-23: 109: 41.49
+	Hs
		441650 ADRB1_HUMAN (13-409): 5.38e-77: 249: 25.62		DLG4_HUMAN (86-493): 2.62e-24: 111: 15.64
+	Mm
		676818 SSR2_MOUSE (33-413): 7.81e-69: 225: 18.86		DLG4_MOUSE (86-477): 2.03e-24: 111: 16.07
+	Mm
		830267 SSR4_MOUSE (23-389): 1.21e-68: 225: 20.57		DLG4_MOUSE (86-477): 2.03e-24: 111: 16.07
+	Mm
		676812 SSR1_MOUSE (39-387): 1.05e-65: 217: 23.10		DLG4_MOUSE (86-477): 2.03e-24: 111: 16.07
+	Rn
		677498 SSR4_RAT (19-389): 5.36e-65: 215: 18.70		DLG4_RAT (86-493): 2.93e-24: 111: 15.40
+	Mm
		830268 SSR4_MOUSE (23-389): 1.21e-68: 225: 20.57		DLG2_MOUSE (393-627): 3.09e-21: 101: 24.48
+	Mm
		676813 SSR1_MOUSE (39-387): 1.05e-65: 217: 23.10		DLG2_MOUSE (393-627): 3.09e-21: 101: 24.48
+	Mm
		897201 DRD2_MOUSE (306-385): 8.26e-15: 78.2: 47.50		DLG4_MOUSE (86-477): 2.03e-24: 111: 16.07