HitPredict

Interactor 1: 5HT2C (P28335)
5-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) (5-HT1C) (Serotonin receptor 2C)
Gene: HTR2C

Interactor 2: LRC8A (Q8IWT6)
Volume-regulated anion channel subunit LRRC8A (Leucine-rich repeat-containing protein 8A) (HsLRRC8A) (Swelling protein 1)
Gene: LRRC8A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 458 Hs			1 810
+	Hs
		658236 5HT2C_HUMAN (1-458): 1.97e-103: 317: 100.00		SCRIB_HUMAN (345-673): 1.08e-54: 207: 25.83
+	Hs
		658286 5HT2C_HUMAN (1-458): 1.97e-103: 317: 100.00		LRRC1_HUMAN (356-696): 1.83e-53: 195: 24.49
+	Hs
		626687 ADA1D_HUMAN (24-447): 1.69e-77: 253: 24.47		SCRIB_HUMAN (345-673): 1.08e-54: 207: 25.83
+	Hs
		676807 SSR1_HUMAN (39-387): 2.15e-64: 214: 23.10		LRC8E_HUMAN (493-808): 2.71e-29: 127: 24.70