HitPredict

Interactor 1: TEAD1 (P28347)
Transcriptional enhancer factor TEF-1 (NTEF-1) (Protein GT-IIC) (TEA domain family member 1) (TEAD-1) (Transcription factor 13) (TCF-13)
Gene: TEAD1

Interactor 2: VGLL4 (Q14135)
Transcription cofactor vestigial-like protein 4 (Vgl-4)
Gene: VGLL4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	1.00	0.930

Property	Details
Experiments	26186194, 28514442, 15140898, 33961781, 35140242
Identification Methods	affinity chromatography technology, two hybrid, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	VGLL4~YBD
Common GO terms	GO:0005634 - nucleus
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 426 Hs			1 290
+	Hs
		1048836 TEAD4_HUMAN (1-426): 0: 725: 74.54		VGLL4_HUMAN (1-290): 6.35e-180: 498: 100.00
+	Hs
		1048842 TEAD3_HUMAN (12-426): 0: 691: 71.23		VGLL4_HUMAN (1-290): 6.35e-180: 498: 100.00
+	Mm
		1143752 TEAD4_MOUSE (1-426): 0: 728: 74.07		VGLL4_MOUSE (23-279): 8.76e-156: 437: 87.94
+	Hs
		1048837 TEAD2_HUMAN (32-426): 0: 631: 67.07		VGLL4_HUMAN (1-290): 6.35e-180: 498: 100.00