HitPredict

Interactor 1: TEAD1 (P28347)
Transcriptional enhancer factor TEF-1 (NTEF-1) (Protein GT-IIC) (TEA domain family member 1) (TEAD-1) (Transcription factor 13) (TCF-13)
Gene: TEAD1

Interactor 2: KMT2C (Q8NEZ4)
Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.364) (Homologous to ALR protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 3)
Gene: KMT2C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 426 Hs			1 4911
+	Hs
		658493 TEAD1_HUMAN (1-426): 0: 782: 100.00		CHD3_HUMAN (390-526): 1.86e-31: 139: 21.38
+	Hs
		1075249 TEAD2_HUMAN (32-426): 0: 631: 67.07		NSD3_HUMAN (1-668): 2.87e-64: 246: 13.52
+	Hs
		658540 TEAD1_HUMAN (1-426): 0: 782: 100.00		REQU_HUMAN (359-435): 2.72e-12: 74.3: 41.25
+	Hs
		152594 TEAD1_HUMAN (1-426): 0: 782: 100.00		KMT2D_HUMAN (2766-3637): 7.14e-09: 65: 8.82
+	Hs
		1059634 TEAD2_HUMAN (32-426): 0: 631: 67.07		CHD4_HUMAN (83-436): 3.08e-38: 161: 13.56