HitPredict

Interactor 1: TEAD1 (P28347)
Transcriptional enhancer factor TEF-1 (NTEF-1) (Protein GT-IIC) (TEA domain family member 1) (TEAD-1) (Transcription factor 13) (TCF-13)
Gene: TEAD1

Interactor 2: VGLL1 (Q99990)
Transcription cofactor vestigial-like protein 1 (Vgl-1) (Protein TONDU)
Gene: VGLL1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	1.00	0.680

Property	Details
Experiments	10518497
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Vg_Tdu~YBD
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 426 Hs			1 258
+	Hs
		1075216 TEAD4_HUMAN (1-426): 0: 725: 74.54		VGLL1_HUMAN (1-258): 5.64e-131: 372: 100.00
+	Hs
		1304846 TEAD3_HUMAN (12-426): 0: 691: 71.23		VGLL1_HUMAN (1-258): 5.64e-131: 372: 100.00
+	Mm
		1143753 TEAD4_MOUSE (1-426): 0: 728: 74.07		VGLL1_MOUSE (1-229): 6.14e-97: 287: 41.50
+	Hs
		1075247 TEAD2_HUMAN (32-426): 0: 631: 67.07		VGLL1_HUMAN (1-258): 5.64e-131: 372: 100.00
+	Mm
		671380 TEAD1_MOUSE (1-426): 0: 783: 99.30		VGLL2_MOUSE (12-209): 6.06e-66: 209: 28.37
+	Hs
		67948 TEAD1_HUMAN (1-426): 0: 782: 100.00		VGLL3_HUMAN (14-171): 8.34e-40: 141: 27.55
+	Hs
		67961 TEAD4_HUMAN (1-426): 0: 725: 74.54		VGLL3_HUMAN (14-171): 8.34e-40: 141: 27.55
+	Hs
		1237699 TEAD3_HUMAN (12-426): 0: 691: 71.23		VGLL2_HUMAN (12-198): 2.69e-51: 171: 29.90
+	Hs
		67994 TEAD3_HUMAN (12-426): 0: 691: 71.23		VGLL3_HUMAN (14-171): 8.34e-40: 141: 27.55
+	Hs
		67962 TEAD2_HUMAN (32-426): 0: 631: 67.07		VGLL3_HUMAN (14-171): 8.34e-40: 141: 27.55