Interactor 1: GBRB3 (P28472)
Gamma-aminobutyric acid receptor subunit beta-3 (GABA(A) receptor subunit beta-3) (GABAAR subunit beta-3)
Gene: GABRB3

Interactor 2: GBRB2 (P47870)
Gamma-aminobutyric acid receptor subunit beta-2 (GABA(A) receptor subunit beta-2) (GABAAR subunit beta-2)
Gene: GABRB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Neur_chan_LBD~Neur_chan_LBD, Neur_chan_LBD~Neur_chan_memb, Neur_chan_memb~Neur_chan_memb
Common GO terms GO:0004890 - GABA-A receptor activity
GO:0005886 - plasma membrane
GO:0007214 - gamma-aminobutyric acid signaling pathway
GO:0022851 - GABA-gated chloride ion channel activity
GO:0030594 - neurotransmitter receptor activity
and 10 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 473
Hs

1 512
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024