HitPredict

Interactor 1: MK01 (P28482)
Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)
Gene: MAPK1

Interactor 2: STA5A (P42229)
Signal transducer and activator of transcription 5A
Gene: STAT5A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	10194762, 10996427
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 360 Hs			1 794
+	Mm
		926434 MK01_MOUSE (10-360): 4.96e-158: 449: 99.72		Q99K94_MOUSE (1-703): 0: 759: 29.30
+	Hs
		658828 MK01_HUMAN (1-360): 2.42e-158: 449: 100.00		STAT1_HUMAN (1-724): 0: 755: 28.09
+	Hs
		658824 MK01_HUMAN (1-360): 2.42e-158: 449: 100.00		STAT3_HUMAN (1-723): 0: 736: 29.94
+	Hs
		647492 MK03_HUMAN (4-358): 3.09e-154: 440: 85.92		STAT3_HUMAN (1-723): 0: 736: 29.94
+	Mm
		786542 MK03_MOUSE (15-357): 1.88e-152: 435: 88.63		STAT3_MOUSE (1-723): 0: 737: 29.94