HitPredict

Interactor 1: CAPZA (P28495)
F-actin-capping protein subunit alpha
Gene: CAP1

Interactor 2: TWF1 (P53250)
Twinfilin-1 (Twinfilin-A)
Gene: TWF1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.651

Property	Details
Experiments	11604420, 37966720, 37968396
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0043332 - mating projection tip GO:0051015 - actin filament binding GO:0051016 - barbed-end actin filament capping
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 268 Sc			1 332
+	Hs
		813067 CAZA2_HUMAN (1-264): 3.38e-124: 356: 29.75		TWF2_HUMAN (1-330): 2.68e-117: 344: 23.30
+	Hs
		857151 CAZA1_HUMAN (1-264): 7.14e-123: 353: 28.32		TWF2_HUMAN (1-330): 2.68e-117: 344: 23.30
+	Hs
		813004 CAZA2_HUMAN (1-264): 3.38e-124: 356: 29.75		TWF1_HUMAN (1-330): 1.28e-114: 337: 23.01
+	Hs
		857109 CAZA1_HUMAN (1-264): 7.14e-123: 353: 28.32		TWF1_HUMAN (1-330): 1.28e-114: 337: 23.01
+	Hs
		618015 CAZA2_HUMAN (1-264): 3.38e-124: 356: 29.75		COF1_HUMAN (4-126): 4.86e-41: 142: 16.28
+	Hs
		813214 CAZA2_HUMAN (1-264): 3.38e-124: 356: 29.75		COF2_HUMAN (2-125): 9.17e-40: 139: 20.00