Interactor 1: LAC1 (P28496)
Ceramide synthase LAC1 (Very-long-chain ceramide synthase LAC1) (EC 2.3.1.297)
Gene: LAC1
Interactor 2: LIP1 (Q03579)
Ceramide synthase subunit LIP1 (LAG1/LAC1-interacting protein 1)
Gene: LIP1
Species: Saccharomyces cerevisiae S288C
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.83 | 0.60 | 0.706 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11283351, 15692566, 37953642, 37968396 |
| Identification Methods | two hybrid pooling approach, affinity chromatography technology, two hybrid, biochemical, x-ray crystallography, pull down, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0046513 - ceramide biosynthetic process GO:0061576 - acyl-CoA ceramide synthase complex |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
