HitPredict

Interactor 1: MAX (P28574)
Protein max (Myc-associated factor X) (Myc-binding novel HLH/LZ protein) (Protein myn)
Gene: MAX

Interactor 2: MXI1 (P50540)
Max-interacting protein 1 (Max interactor 1)
Gene: MXI1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	20946988
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	HLH~HLH
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription GO:0006357 - regulation of transcription by RNA polymerase II and 1 others more... GO:0046983 - protein dimerization activity
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 160 Mm			1 228
+	Hs
		840202 MAX_HUMAN (1-160): 1.08e-30: 110: 99.38		MXI1_HUMAN (1-228): 7.93e-92: 270: 96.05
+	Hs
		983441 MNT_HUMAN (7-152): 1.58e-29: 114: 23.90		MAD1_HUMAN (7-223): 4.84e-62: 195: 58.07
+	Hs
		1304736 MNT_HUMAN (7-152): 1.58e-29: 114: 23.90		MAD3_HUMAN (8-193): 3.05e-49: 161: 49.47
+	Rn
		449464 MAX_RAT (1-160): 2.95e-32: 114: 99.38		MYC_RAT (27-150): 9.36e-39: 141: 28.03
+	Hs
		1304735 MNT_HUMAN (7-152): 1.58e-29: 114: 23.90		MNT_HUMAN (42-184): 1.88e-37: 139: 29.94
+	Hs
		347688 MNT_HUMAN (7-152): 1.58e-29: 114: 23.90		MYC_HUMAN (27-150): 6.97e-38: 138: 28.03
+	Mm
		348406 MAX_MOUSE (1-160): 1.21e-31: 112: 100.00		MYC_MOUSE (27-150): 3.13e-38: 139: 28.03
+	Hs
		346390 MAX_HUMAN (1-160): 1.08e-30: 110: 99.38		MYC_HUMAN (27-150): 6.97e-38: 138: 28.03
+	Mm
		372842 MAX_MOUSE (1-160): 1.21e-31: 112: 100.00		MYCN_MOUSE (27-148): 2.79e-36: 134: 23.88
+	Hs
		379188 MAX_HUMAN (1-160): 1.08e-30: 110: 99.38		MYCN_HUMAN (27-148): 4.9e-35: 131: 23.88
+	Hs
		607791 SRBP1_HUMAN (9-149): 7.47e-29: 113: 23.08		USF1_HUMAN (39-158): 7.36e-35: 127: 22.22
+	Hs
		607801 MAX_HUMAN (1-160): 1.08e-30: 110: 99.38		USF1_HUMAN (39-158): 7.36e-35: 127: 22.22
+	Mm
		139904 MNT_MOUSE (7-152): 1.23e-32: 123: 23.90		MAX_MOUSE (60-166): 5.19e-23: 93: 19.63
+	Mm
		486429 MAX_MOUSE (1-160): 1.21e-31: 112: 100.00		MYCL_MOUSE (25-149): 3.76e-24: 100: 23.90
+	Hs
		519709 MAX_HUMAN (1-160): 1.08e-30: 110: 99.38		MYCL_HUMAN (45-149): 3.88e-25: 102: 27.78
+	Hs
		898182 MNT_HUMAN (7-152): 1.58e-29: 114: 23.90		MAX_HUMAN (60-166): 2.04e-22: 91.4: 19.63
+	Hs
		898090 MAX_HUMAN (1-160): 1.08e-30: 110: 99.38		MAX_HUMAN (60-166): 2.04e-22: 91.4: 19.63
+	Hs
		1016055 SRBP2_HUMAN (19-153): 9.79e-32: 121: 24.27		SRBP2_HUMAN (32-138): 6.68e-12: 66.4: 25.23
+	Hs
		738962 SRBP1_HUMAN (9-149): 7.47e-29: 113: 23.08		SRBP2_HUMAN (32-138): 6.68e-12: 66.4: 25.23