HitPredict

Interactor 1: MAX (P28574)
Protein max (Myc-associated factor X) (Myc-binding novel HLH/LZ protein) (Protein myn)
Gene: MAX

Interactor 2: PCGF6 (Q99NA9)
Polycomb group RING finger protein 6 (Mel18 and Bmi1-like RING finger) (RING finger protein 134)
Gene: PCGF6

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	20946988
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 160 Mm			1 353
+	Hs
		898188 MAX_HUMAN (1-160): 1.08e-30: 110: 99.38		PCGF6_HUMAN (45-353): 1.29e-79: 249: 93.55
+	Hs
		347818 MYC_HUMAN (11-107): 8.31e-25: 100: 33.00		PCGF6_HUMAN (45-353): 1.29e-79: 249: 93.55
+	Hs
		585632 TFE3_HUMAN (11-147): 1.64e-24: 100: 19.72		BMI1_HUMAN (120-352): 9.29e-64: 207: 34.71
+	Hs
		379067 MYCN_HUMAN (9-100): 6.86e-21: 89.9: 32.26		BMI1_HUMAN (120-352): 9.29e-64: 207: 34.71
+	Hs
		347755 MYC_HUMAN (11-107): 8.31e-25: 100: 33.00		PCGF1_HUMAN (120-350): 1.98e-55: 183: 35.90
+	Mm
		659355 MAX_MOUSE (1-160): 1.21e-31: 112: 100.00		RING2_MOUSE (106-306): 2.34e-36: 136: 16.67
+	Hs
		898178 MAX_HUMAN (1-160): 1.08e-30: 110: 99.38		RING2_HUMAN (106-306): 2.95e-36: 135: 16.67
+	Hs
		347679 MYC_HUMAN (11-107): 8.31e-25: 100: 33.00		RING2_HUMAN (106-306): 2.95e-36: 135: 16.67
+	Hs
		584889 SRBP1_HUMAN (9-149): 7.47e-29: 113: 23.08		RO52_HUMAN (123-312): 2.23e-30: 122: 17.80
+	Hs
		379766 MYCN_HUMAN (9-100): 6.86e-21: 89.9: 32.26		RING2_HUMAN (106-306): 2.95e-36: 135: 16.67
+	Hs
		347835 MYC_HUMAN (11-107): 8.31e-25: 100: 33.00		TRIM6_HUMAN (128-340): 4.53e-31: 124: 17.80
+	Hs
		345897 MYC_HUMAN (11-107): 8.31e-25: 100: 33.00		RO52_HUMAN (123-312): 2.23e-30: 122: 17.80
+	Hs
		898110 MAX_HUMAN (1-160): 1.08e-30: 110: 99.38		RING1_HUMAN (106-234): 9.51e-27: 111: 21.54
+	Hs
		282453 MYC_HUMAN (11-107): 8.31e-25: 100: 33.00		RNF8_HUMAN (46-220): 3.9e-29: 118: 23.73
+	Hs
		346606 MYC_HUMAN (11-107): 8.31e-25: 100: 33.00		RING1_HUMAN (106-234): 9.51e-27: 111: 21.54
+	Hs
		379317 MYCN_HUMAN (9-100): 6.86e-21: 89.9: 32.26		RING1_HUMAN (106-234): 9.51e-27: 111: 21.54