HitPredict

Interactor 1: KCC2B (P28652)
Calcium/calmodulin-dependent protein kinase type II subunit beta (CaM kinase II subunit beta) (CaMK-II subunit beta) (EC 2.7.11.17)
Gene: Camk2b

Interactor 2: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Species: Mus musculus

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.839

The method score is based on:

Property Details
Experiments 27507650, 28671696, 28469556
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~Pkinase, Pkinase~SAM_1
Common GO terms GO:0005737 - cytoplasm
GO:0014069 - postsynaptic density
GO:0043005 - neuron projection
GO:0050885 - neuromuscular process controlling balance
GO:0060291 - long-term synaptic potentiation
and 1 others

more...
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 542
Mm

1 1730
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Last updated: 15 Jul 2024