HitPredict

Interactor 1: NCKP1 (P28660)
Nck-associated protein 1 (NAP 1) (Brain protein H19) (MH19) (Membrane-associated protein HEM-2) (p125Nap1)
Gene: Nckap1

Interactor 2: ABI2 (P62484)
Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1)
Gene: ABI2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Abi_HHR~Nckap1
Common GO terms	GO:0016477 - cell migration GO:0030027 - lamellipodium GO:0031209 - SCAR complex
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1128 Mm			1 446
+	Mm
		659529 NCKP1_MOUSE (1-1128): 0: 1695: 100.00		ABI1_MOUSE (1-446): 9.86e-108: 329: 61.24
+	Hs
		1224661 NCKP1_HUMAN (1-1128): 0: 1693: 99.38		ABI1_HUMAN (1-446): 3.25e-104: 320: 59.61
+	Hs
		1348436 NCKP1_HUMAN (1-1128): 0: 1693: 99.38		ABI2_HUMAN (1-446): 1.6e-93: 293: 79.92
+	Mm
		561153 NCKP1_MOUSE (1-1128): 0: 1695: 100.00		SPTN1_MOUSE (2-443): 9.46e-53: 193: 13.23
+	Mm
		82749 NCKP1_MOUSE (1-1128): 0: 1695: 100.00		B9EKJ1_MOUSE (2-443): 7.39e-53: 193: 13.23
+	Mm
		1208100 NCKPL_MOUSE (4-1121): 0: 1527: 58.79		ABI1_MOUSE (1-446): 9.86e-108: 329: 61.24
+	Hs
		876303 NCKPL_HUMAN (4-1121): 0: 1561: 59.14		ABI2_HUMAN (1-446): 1.6e-93: 293: 79.92
+	Dm
		876317 HEM_DROME (1-1122): 0: 1546: 59.66		Q9Y0S9_DROME (1-442): 2.49e-75: 245: 37.85
+	Mm
		1207370 Q8BVQ3_MOUSE (811-1121): 7.79e-137: 418: 60.77		ABI1_MOUSE (1-446): 9.86e-108: 329: 61.24