HitPredict

Interactor 1: SNAB (P28663)
Beta-soluble NSF attachment protein (SNAP-beta) (Brain protein I47) (N-ethylmaleimide-sensitive factor attachment protein beta)
Gene: Napb

Interactor 2: VAMP2 (P63044)
Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
Gene: VAMP2

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	20114047
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	SNAP~Synaptobrevin
Common GO terms	GO:0000149 - SNARE binding GO:0019905 - syntaxin binding GO:0048488 - synaptic vesicle endocytosis GO:0070044 - synaptobrevin 2-SNAP-25-syntaxin-1a complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 298 Mm			1 116
+	Hs
		261720 SNAB_HUMAN (1-298): 3.42e-116: 338: 100.00		VAMP4_HUMAN (18-99): 1.7e-26: 97.4: 35.37
+	Hs
		850546 SNAA_HUMAN (1-293): 7.24e-109: 319: 83.96		VAMP7_HUMAN (3-96): 6.18e-30: 108: 30.30
+	Hs
		306867 SNAB_HUMAN (1-298): 3.42e-116: 338: 100.00		VAMP5_HUMAN (31-98): 1.79e-22: 86.3: 41.18
+	Dm
		1095560 SNAP_DROME (5-292): 1.02e-103: 306: 62.15		Q7JYX5_DROME (6-111): 6.97e-34: 118: 22.52
+	Dm
		577215 SNAP_DROME (5-292): 1.02e-103: 306: 62.15		SYB_DROME (7-115): 1.17e-32: 113: 57.02
+	Hs
		261646 SNAA_HUMAN (1-293): 7.24e-109: 319: 83.96		VAMP4_HUMAN (18-99): 1.7e-26: 97.4: 35.37
+	Hs
		873528 SNAA_HUMAN (1-293): 7.24e-109: 319: 83.96		VAMP2_HUMAN (25-116): 6.75e-25: 92.4: 100.00
+	Hs
		873545 SNAA_HUMAN (1-293): 7.24e-109: 319: 83.96		VAMP3_HUMAN (26-98): 6.78e-24: 89.3: 91.78
+	Hs
		873576 SNAA_HUMAN (1-293): 7.24e-109: 319: 83.96		VAMP8_HUMAN (23-99): 9e-24: 89.3: 33.77
+	Hs
		263203 SNAA_HUMAN (1-293): 7.24e-109: 319: 83.96		SC22B_HUMAN (25-115): 3.54e-22: 88.1: 21.98
+	Hs
		306778 SNAA_HUMAN (1-293): 7.24e-109: 319: 83.96		VAMP5_HUMAN (31-98): 1.79e-22: 86.3: 41.18
+	Zm
		31296 A0A1D6PZ82_MAIZE (5-272): 1.43e-88: 269: 37.55		A0A1D6KH00_MAIZE (2-111): 1.07e-35: 130: 32.14
+	Dm
		115802 SNAP_DROME (5-292): 1.02e-103: 306: 62.15		M9PGI6_DROME (24-112): 8.9e-21: 84.7: 24.72
+	Sc
		696608 SEC17_YEAST (8-293): 1.6e-85: 260: 33.56		NYV1_YEAST (14-115): 7.76e-26: 98.6: 25.49
+	Sc
		678143 SEC17_YEAST (8-293): 1.6e-85: 260: 33.56		SNC1_YEAST (6-98): 2.31e-25: 93.6: 32.98
+	Hs
		850592 SNAG_HUMAN (4-251): 6.3e-69: 218: 24.30		VAMP7_HUMAN (3-96): 6.18e-30: 108: 30.30
+	Hs
		261710 SNAG_HUMAN (4-251): 6.3e-69: 218: 24.30		VAMP4_HUMAN (18-99): 1.7e-26: 97.4: 35.37
+	Hs
		926249 SNAG_HUMAN (4-251): 6.3e-69: 218: 24.30		VAMP2_HUMAN (25-116): 6.75e-25: 92.4: 100.00
+	Hs
		263338 SNAG_HUMAN (4-251): 6.3e-69: 218: 24.30		SC22B_HUMAN (25-115): 3.54e-22: 88.1: 21.98
+	Hs
		306855 SNAG_HUMAN (4-251): 6.3e-69: 218: 24.30		VAMP5_HUMAN (31-98): 1.79e-22: 86.3: 41.18