Interactor 1: RXRA (P28700)
Retinoic acid receptor RXR-alpha (Nuclear receptor subfamily 2 group B member 1) (Retinoid X receptor alpha)
Gene: RXRA

Interactor 2: THA (P63058)
Thyroid hormone receptor alpha (Nuclear receptor subfamily 1 group A member 1) (c-erbA-1) (c-erbA-alpha)
Gene: Thra

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.34 1.00 0.590

The method score is based on:

Property Details
Experiments 16936638
Identification Methods two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Hormone_recep~Hormone_recep, Hormone_recep~zf-C4, zf-C4~zf-C4
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0002157 - positive regulation of thyroid hormone receptor signaling pathway
GO:0004879 - nuclear receptor activity
GO:0005634 - nucleus
and 10 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 467
Mm

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024