HitPredict

Interactor 1: RXRA (P28700)
Retinoic acid receptor RXR-alpha (Nuclear receptor subfamily 2 group B member 1) (Retinoid X receptor alpha)
Gene: RXRA

Interactor 2: SQSTM (Q64337)
Sequestosome-1 (STONE14) (Ubiquitin-binding protein p62)
Gene: Sqstm1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	27728806
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005739 - mitochondrion GO:0008270 - zinc ion binding GO:0030154 - cell differentiation GO:0044877 - protein-containing complex binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 467 Mm			1 442
+	Hs
		587164 RXRA_HUMAN (1-467): 1.59e-177: 507: 97.43		SQSTM_HUMAN (1-442): 0: 715: 89.82
+	Hs
		369546 ESR1_HUMAN (1-464): 8.76e-114: 349: 23.56		SQSTM_HUMAN (1-442): 0: 715: 89.82
+	Hs
		487961 RARA_HUMAN (48-462): 3.24e-112: 340: 28.67		SQSTM_HUMAN (1-442): 0: 715: 89.82
+	Hs
		611436 NR4A1_HUMAN (3-460): 5.09e-106: 329: 27.37		SQSTM_HUMAN (1-442): 0: 715: 89.82
+	Hs
		1036772 ESR2_HUMAN (15-463): 4.52e-106: 327: 25.31		SQSTM_HUMAN (1-442): 0: 715: 89.82
+	Hs
		1206010 ESR2_HUMAN (15-463): 4.52e-106: 327: 25.31		MIB1_HUMAN (105-228): 1.65e-27: 117: 27.69
+	Hs
		319689 ESR1_HUMAN (1-464): 8.76e-114: 349: 23.56		HERC2_HUMAN (120-197): 1.35e-11: 69: 32.50
+	Hs
		319950 ESR2_HUMAN (15-463): 4.52e-106: 327: 25.31		HERC2_HUMAN (120-197): 1.35e-11: 69: 32.50