HitPredict

Interactor 1: RBL1 (P28749)
Retinoblastoma-like protein 1 (107 kDa retinoblastoma-associated protein) (p107) (pRb1)
Gene: RBL1

Interactor 2: E2F1 (Q01094)
Transcription factor E2F1 (E2F-1) (PBR3) (Retinoblastoma-associated protein 1) (RBAP-1) (Retinoblastoma-binding protein 3) (RBBP-3) (pRB-binding protein E2F-1)
Gene: E2F1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.967

The method score is based on:

Property Details
Experiments 9501179, 12401786, 8230483, 1530885, 8458319, 8657117, 12096339, 23853093, 34591642
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains E2F_CC-MB~Rb_C
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0005654 - nucleoplasm
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1068
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024