HitPredict

Interactor 1: TNR8 (P28908)
Tumor necrosis factor receptor superfamily member 8 (CD30L receptor) (Ki-1 antigen) (Lymphocyte activation antigen CD30) (CD antigen CD30)
Gene: TNFRSF8

Interactor 2: CDC6 (Q99741)
Cell division control protein 6 homolog (CDC6-related protein) (Cdc18-related protein) (HsCdc18) (p62(cdc6)) (HsCDC6)
Gene: CDC6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0008285 - negative regulation of cell population proliferation
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 595 Hs			1 560
+	Hs
		591396 TNR1B_HUMAN (12-239): 1.19e-49: 180: 26.16		CDC6_HUMAN (1-560): 1.83e-166: 486: 100.00
+	Hs
		584460 TNR1A_HUMAN (22-194): 7.64e-40: 153: 19.02		CDC6_HUMAN (1-560): 1.83e-166: 486: 100.00
+	Hs
		121527 TR10A_HUMAN (21-159): 1.51e-28: 121: 20.57		CDC6_HUMAN (1-560): 1.83e-166: 486: 100.00
+	Hs
		591323 TNR1B_HUMAN (12-239): 1.19e-49: 180: 26.16		ORC1_HUMAN (4-548): 3.74e-94: 308: 22.62
+	Hs
		217760 TNF6B_HUMAN (38-204): 4.29e-43: 158: 25.29		ORC4_HUMAN (143-552): 5.24e-66: 222: 14.49
+	Hs
		217776 TNR5_HUMAN (3-247): 2.73e-38: 144: 16.85		ORC4_HUMAN (143-552): 5.24e-66: 222: 14.49
+	Hs
		639556 TNR5_HUMAN (3-247): 2.73e-38: 144: 16.85		RFC5_HUMAN (162-518): 3.37e-64: 215: 17.04