HitPredict

Interactor 1: CD1B (P29016)
T-cell surface glycoprotein CD1b (CD antigen CD1b)
Gene: CD1B

Interactor 2: B2MG (P61769)
Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]
Gene: B2M

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.926

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 12118248, 14764708
Identification Methods affinity chromatography technology, x-ray crystallography, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains C1-set~C1-set, C1-set~MHC_I_3
Common GO terms GO:0001916 - positive regulation of T cell mediated cytotoxicity
GO:0005615 - extracellular space
GO:0005765 - lysosomal membrane
GO:0005794 - Golgi apparatus
GO:0005829 - cytosol
and 3 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024