HitPredict

Interactor 1: S10A2 (P29034)
Protein S100-A2 (CAN19) (Protein S-100L) (S100 calcium-binding protein A2)
Gene: S100A2

Interactor 2: S10A2 (P29034)
Protein S100-A2 (CAN19) (Protein S-100L) (S100 calcium-binding protein A2)
Gene: S100A2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	1.00	0.953

Property	Details
Experiments	25416956, 16189514, 32296183, 10951287, unassigned1304, 22394450
Identification Methods	two hybrid, affinity chromatography technology, two hybrid array, two hybrid prey pooling approach, validated two hybrid, two hybrid pooling approach, x-ray crystallography
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	S_100~S_100
Common GO terms	GO:0005509 - calcium ion binding GO:0043542 - endothelial cell migration GO:0046914 - transition metal ion binding GO:0048306 - calcium-dependent protein binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 98 Hs			1 98
+	Hs
		1135040 Q5T7Y6_HUMAN (2-91): 3.08e-40: 131: 52.22		Q5T7Y6_HUMAN (2-91): 3.08e-40: 131: 52.22
+	Mm
		421245 S10A4_MOUSE (2-97): 2.1e-39: 128: 61.46		S10A4_MOUSE (2-97): 2.1e-39: 128: 61.46
+	Hs
		642916 S10A2_HUMAN (1-98): 9.73e-40: 128: 100.00		S10A4_HUMAN (2-97): 2.05e-38: 125: 61.46
+	Hs
		615204 S10A2_HUMAN (1-98): 9.73e-40: 128: 100.00		S10A1_HUMAN (2-91): 3.92e-38: 124: 52.22
+	Mm
		421246 S10A4_MOUSE (2-97): 2.1e-39: 128: 61.46		S10A1_MOUSE (2-91): 2.19e-37: 122: 51.11
+	Hs
		642915 S10A4_HUMAN (2-97): 2.05e-38: 125: 61.46		S10A4_HUMAN (2-97): 2.05e-38: 125: 61.46
+	Hs
		615203 S10A4_HUMAN (2-97): 2.05e-38: 125: 61.46		S10A1_HUMAN (2-91): 3.92e-38: 124: 52.22
+	Hs
		638981 Q5T7Y6_HUMAN (2-91): 3.08e-40: 131: 52.22		S100P_HUMAN (4-92): 8.31e-36: 118: 42.70
+	Hs
		615200 S10A1_HUMAN (2-91): 3.92e-38: 124: 52.22		S10A1_HUMAN (2-91): 3.92e-38: 124: 52.22
+	Hs
		661208 S10A2_HUMAN (1-98): 9.73e-40: 128: 100.00		S10A3_HUMAN (2-98): 3.78e-36: 119: 43.30
+	Hs
		615206 S10A1_HUMAN (2-91): 3.92e-38: 124: 52.22		S10A3_HUMAN (2-98): 3.78e-36: 119: 43.30
+	Hs
		380790 Q5T7Y6_HUMAN (2-91): 3.08e-40: 131: 52.22		S100B_HUMAN (4-92): 8.65e-33: 111: 44.94
+	Hs
		615201 S10A1_HUMAN (2-91): 3.92e-38: 124: 52.22		S100P_HUMAN (4-92): 8.31e-36: 118: 42.70
+	Hs
		380742 S10A2_HUMAN (1-98): 9.73e-40: 128: 100.00		S100B_HUMAN (4-92): 8.65e-33: 111: 44.94
+	Hs
		380739 S10A4_HUMAN (2-97): 2.05e-38: 125: 61.46		S100B_HUMAN (4-92): 8.65e-33: 111: 44.94
+	Hs
		380736 S10A1_HUMAN (2-91): 3.92e-38: 124: 52.22		S100B_HUMAN (4-92): 8.65e-33: 111: 44.94
+	Hs
		416574 S10A4_HUMAN (2-97): 2.05e-38: 125: 61.46		S10A6_HUMAN (2-93): 1.75e-30: 104: 46.74