Interactor 1: A8K2M0 (A8K2M0)
26S proteasome regulatory subunit 6B (26S proteasome AAA-ATPase subunit RPT3) (Proteasome 26S subunit ATPase 4)
Gene: PSMC4

Interactor 2: PSMD2 (Q13200)
26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97) (Protein 55.11) (Tumor necrosis factor type 1 receptor-associated protein 2)
Gene: PSMD2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 25036637
Identification Methods luminescence based mammalian interactome mapping
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA_lid_3~RPN1_C, AAA_lid_3~RPN1_RPN2_N
Common GO terms GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0008540 - proteasome regulatory particle, base subcomplex
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 418
Hs

1 908
+ Hs
+ Hs
+ At
+ At
+ At
+ At
+ At
+ Dm
+ Sp
+ Ce
+ Sc
+ Hs
+ At
+ At
+ Hs
+ Hs
+ Dm
+ Hs
+ Sp
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024