HitPredict

Interactor 1: TF3B (P29056)
Transcription factor IIIB 70 kDa subunit (TFIIIB) (B-related factor 1) (BRF-1)
Gene: BRF1

Interactor 2: TFC4 (P33339)
Transcription factor tau 131 kDa subunit (TFIIIC 131 kDa subunit) (Transcription factor C subunit 4)
Gene: TFC4

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	0.60	0.744

Property	Details
Experiments	10393904, 7797524, 12930823, 10329159, 12167707, 10859316, 10559229, 16880507
Identification Methods	two hybrid, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006383 - transcription by RNA polymerase III
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 596 Sc			1 1025
+	Sc
		661789 TF2B_YEAST (4-287): 2.65e-88: 279: 17.13		TFC4_YEAST (1-1025): 7.67e-180: 552: 100.00
+	Sp
		251516 TF3B_SCHPO (4-595): 1.65e-135: 406: 36.18		SFC4_SCHPO (13-1024): 1.8e-123: 403: 21.05
+	Hs
		1273566 TF3B_HUMAN (3-594): 0: 534: 28.90		TF3C3_HUMAN (108-493): 5.13e-30: 130: 17.77
+	Sc
		542108 TF2B_YEAST (4-287): 2.65e-88: 279: 17.13		CYC8_YEAST (125-279): 6.93e-12: 71.9: 20.51
+	Sc
		571880 TF2B_YEAST (4-287): 2.65e-88: 279: 17.13		SKI3_YEAST (3-478): 8.67e-12: 71.7: 10.39
+	Sc
		661983 TF2B_YEAST (4-287): 2.65e-88: 279: 17.13		CDC27_YEAST (131-385): 7.67e-12: 71.5: 12.50