HitPredict

Interactor 1: PTN4 (P29074)
Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (MEG) (PTPase-MEG1)
Gene: PTPN4

Interactor 2: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	27432908, 28330616, 28675297
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 926 Hs			1 246
+	Hs
		663970 PTN4_HUMAN (1-926): 0: 949: 100.00		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		663973 PTN4_HUMAN (1-926): 0: 949: 100.00		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		646653 PTN4_HUMAN (1-926): 0: 949: 100.00		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		663969 PTN4_HUMAN (1-926): 0: 949: 100.00		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		663976 PTN4_HUMAN (1-926): 0: 949: 100.00		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51
+	Hs
		640229 PTN3_HUMAN (1-923): 0: 817: 50.53		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		640216 PTN3_HUMAN (1-923): 0: 817: 50.53		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		640230 PTN3_HUMAN (1-923): 0: 817: 50.53		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		640212 PTN3_HUMAN (1-923): 0: 817: 50.53		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		640228 PTN3_HUMAN (1-923): 0: 817: 50.53		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		640237 PTN3_HUMAN (1-923): 0: 817: 50.53		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51
+	Hs
		640217 PTN3_HUMAN (1-923): 0: 817: 50.53		1433S_HUMAN (3-239): 3.38e-100: 293: 68.62
+	Hs
		910025 E41L1_HUMAN (12-647): 6.92e-145: 453: 27.85		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		683710 E41L1_HUMAN (12-647): 6.92e-145: 453: 27.85		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		927524 E41L1_HUMAN (12-647): 6.92e-145: 453: 27.85		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		683836 E41L3_HUMAN (21-682): 1.53e-132: 427: 27.22		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		647274 E41L1_HUMAN (12-647): 6.92e-145: 453: 27.85		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		647400 E41L3_HUMAN (21-682): 1.53e-132: 427: 27.22		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		905110 E41L1_HUMAN (12-647): 6.92e-145: 453: 27.85		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		982496 E41L1_HUMAN (12-647): 6.92e-145: 453: 27.85		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51