Interactor 1: T2EA (P29083)
General transcription factor IIE subunit 1 (General transcription factor IIE 56 kDa subunit) (Transcription initiation factor IIE subunit alpha) (TFIIE-alpha)
Gene: GTF2E1

Interactor 2: TF2H1 (P32780)
General transcription factor IIH subunit 1 (Basic transcription factor 2 62 kDa subunit) (BTF2 p62) (General transcription factor IIH polypeptide 1) (TFIIH basal transcription factor complex p62 subunit)
Gene: GTF2H1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 1.00 0.933

The method score is based on:

Property Details
Experiments 32296183, 18160537, 18354501, 25492609, unassigned1304
Identification Methods two hybrid, pull down, x-ray crystallography, isothermal titration calorimetry, two hybrid prey pooling approach, two hybrid array, nuclear magnetic resonance, validated two hybrid
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains BSD~TFIIE-A_C, PH_TFIIH~TFIIE-A_C
Common GO terms GO:0005654 - nucleoplasm
GO:0006366 - transcription by RNA polymerase II
GO:0006367 - transcription initiation at RNA polymerase II promoter
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 439
Hs

1 548
+ Sp
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024