HitPredict

Interactor 1: NTCA (P29283)
Global nitrogen regulator
Gene: NTCA

Interactor 2: NTCA (P29283)
Global nitrogen regulator
Gene: NTCA

Species: Synechococcus elongatus PCC 7942 = FACHB-805

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	20716687
Identification Methods	x-ray crystallography
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	cNMP_binding~cNMP_binding, HTH_Crp_2~cNMP_binding, HTH_Crp_2~HTH_Crp_2
Common GO terms	GO:0003677 - DNA binding GO:0003700 - DNA-binding transcription factor activity GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 222 Se			1 222
+	Ns
		457277 NTCA_NOSS1 (1-222): 2.15e-60: 190: 77.03		NTCA_NOSS1 (1-222): 2.15e-60: 190: 77.03
+	Ec
		467295 CRP_ECOLI (21-215): 9.41e-52: 167: 25.51		CRP_ECOLI (21-215): 9.41e-52: 167: 25.51
+	Pa
		877180 VFR_PSEAE (6-215): 7.16e-51: 166: 22.07		VFR_PSEAE (6-215): 7.16e-51: 166: 22.07
+	Hs
		1356780 HCN2_HUMAN (3-198): 7.33e-35: 132: 17.16		HCN2_HUMAN (3-198): 7.33e-35: 132: 17.16
+	Mm
		292102 HCN2_MOUSE (3-198): 1.28e-34: 132: 17.16		HCN2_MOUSE (3-198): 1.28e-34: 132: 17.16
+	Hs
		1356781 HCN2_HUMAN (3-198): 7.33e-35: 132: 17.16		HCN4_HUMAN (3-165): 2.07e-34: 131: 18.71
+	Hs
		1377721 HCN4_HUMAN (3-165): 2.07e-34: 131: 18.71		HCN4_HUMAN (3-165): 2.07e-34: 131: 18.71
+	Mm
		71335 HCN2_MOUSE (3-198): 1.28e-34: 132: 17.16		B2RY58_MOUSE (3-151): 2.71e-34: 130: 20.38
+	At
		1105412 AKT1_ARATH (1-155): 1.18e-33: 129: 13.75		AKT1_ARATH (1-155): 1.18e-33: 129: 13.75
+	At
		1105413 AKT1_ARATH (1-155): 1.18e-33: 129: 13.75		KAT1_ARATH (1-205): 2.98e-33: 127: 15.17
+	At
		1107042 KAT1_ARATH (1-205): 2.98e-33: 127: 15.17		KAT1_ARATH (1-205): 2.98e-33: 127: 15.17
+	Hs
		240252 HCN2_HUMAN (3-198): 7.33e-35: 132: 17.16		HCN1_HUMAN (3-142): 6.86e-30: 118: 19.31
+	Mm
		292103 HCN2_MOUSE (3-198): 1.28e-34: 132: 17.16		HCN1_MOUSE (3-142): 6.9e-30: 118: 19.31
+	Hs
		240287 HCN4_HUMAN (3-165): 2.07e-34: 131: 18.71		HCN1_HUMAN (3-142): 6.86e-30: 118: 19.31
+	Mm
		71336 B2RY58_MOUSE (3-151): 2.71e-34: 130: 20.38		HCN1_MOUSE (3-142): 6.9e-30: 118: 19.31
+	Hs
		1349966 HCN4_HUMAN (3-165): 2.07e-34: 131: 18.71		HCN3_HUMAN (5-145): 2.37e-29: 116: 17.81
+	Mm
		251014 HCN4_MOUSE (3-156): 1.59e-33: 129: 18.87		HCN1_MOUSE (3-142): 6.9e-30: 118: 19.31