HitPredict

Interactor 1: HRR25 (P29295)
Casein kinase I homolog HRR25 (EC 2.7.11.1)
Gene: HRR25

Interactor 2: ELP2 (P42935)
Elongator complex protein 2 (Gamma-toxin target 2)
Gene: ELP2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.689

Property	Details
Experiments	25569479, 12628929, 30275269, 21460040
Identification Methods	affinity chromatography technology, pull down, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0002098 - tRNA wobble uridine modification GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 494 Sc			1 788
+	Hs
		822233 KC1D_HUMAN (1-412): 9e-131: 387: 50.12		WDR5_HUMAN (592-786): 2.57e-39: 150: 20.51
+	Hs
		1038897 KCC2B_HUMAN (4-490): 1.43e-123: 377: 13.80		WDR5B_HUMAN (194-590): 1.51e-40: 154: 14.07
+	Hs
		830319 KC1E_HUMAN (1-398): 1.33e-127: 379: 51.47		WDR5_HUMAN (592-786): 2.57e-39: 150: 20.51
+	Mm
		1206794 KC1A_MOUSE (2-327): 1.94e-123: 365: 58.28		FBXW7_MOUSE (2-229): 1.48e-39: 158: 16.23
+	Hs
		822121 KC1A_HUMAN (2-327): 1.94e-123: 365: 58.28		FBXW7_HUMAN (2-229): 3.58e-39: 157: 16.23
+	Hs
		821966 KC1A_HUMAN (2-327): 1.94e-123: 365: 58.28		WDR5_HUMAN (592-786): 2.57e-39: 150: 20.51
+	Hs
		1236899 KC1AL_HUMAN (2-329): 1.54e-118: 353: 55.18		FBXW7_HUMAN (2-229): 3.58e-39: 157: 16.23
+	Hs
		822292 KC1D_HUMAN (1-412): 9e-131: 387: 50.12		ELP2_HUMAN (431-783): 1.91e-19: 95.8: 12.59
+	Dm
		870293 KC1A_DROME (2-319): 1.08e-130: 384: 57.55		Q9VDE3_DROME (27-145): 2.44e-10: 65.6: 24.60
+	Hs
		830452 KC1E_HUMAN (1-398): 1.33e-127: 379: 51.47		WDR90_HUMAN (425-787): 2.9e-11: 69.5: 13.57
+	Dm
		283743 DCO_DROME (1-318): 6.01e-122: 365: 61.01		Q9VDE3_DROME (27-145): 2.44e-10: 65.6: 24.60