HitPredict

Interactor 1: EPHA2 (P29317)
Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)
Gene: EPHA2

Interactor 2: RAB9A (P51151)
Ras-related protein Rab-9A
Gene: RAB9A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	29568061, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~fn3
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 976 Hs			1 201
+	Hs
		665242 EPHA2_HUMAN (1-976): 0: 1141: 100.00		RAB35_HUMAN (1-201): 1.97e-87: 257: 36.72
+	Hs
		665174 EPHA2_HUMAN (1-976): 0: 1141: 100.00		RAB7A_HUMAN (2-200): 5.12e-86: 254: 50.24
+	Hs
		1070202 EPHA7_HUMAN (4-974): 0: 1128: 50.30		RAB35_HUMAN (1-201): 1.97e-87: 257: 36.72
+	Hs
		665197 EPHA2_HUMAN (1-976): 0: 1141: 100.00		RB11A_HUMAN (3-201): 3.4e-75: 227: 35.38
+	Hs
		665398 EPHA3_HUMAN (24-976): 0: 1111: 51.19		RAB35_HUMAN (1-201): 1.97e-87: 257: 36.72
+	Hs
		665604 EPHB2_HUMAN (28-973): 0: 1089: 48.29		RAB35_HUMAN (1-201): 1.97e-87: 257: 36.72
+	Hs
		665456 EPHA8_HUMAN (28-975): 0: 1049: 46.72		RAB7A_HUMAN (2-200): 5.12e-86: 254: 50.24
+	Hs
		665466 EPHA8_HUMAN (28-975): 0: 1049: 46.72		RB11A_HUMAN (3-201): 3.4e-75: 227: 35.38
+	Hs
		872534 EPHB4_HUMAN (14-970): 0: 986: 44.99		RAB35_HUMAN (1-201): 1.97e-87: 257: 36.72
+	Rn
		451802 INSR_RAT (371-873): 7.71e-134: 438: 29.49		RAB7A_RAT (2-199): 5.29e-86: 254: 50.25
+	Hs
		411350 INSR_HUMAN (281-933): 1.71e-136: 445: 24.85		RB11A_HUMAN (3-201): 3.4e-75: 227: 35.38
+	Rn
		102471 INSR_RAT (371-873): 7.71e-134: 438: 29.49		G3V6H0_RAT (2-201): 4.9e-77: 231: 32.51
+	Rn
		544805 INSR_RAT (371-873): 7.71e-134: 438: 29.49		RB11A_RAT (3-201): 3.4e-75: 227: 35.38
+	Hs
		435598 IGF1R_HUMAN (393-877): 8.17e-134: 437: 30.00		RB11A_HUMAN (3-201): 3.4e-75: 227: 35.38
+	Rn
		192819 INSR_RAT (371-873): 7.71e-134: 438: 29.49		RB11B_RAT (3-201): 6.93e-74: 223: 32.71
+	Hs
		433769 LYN_HUMAN (607-879): 2.06e-64: 228: 42.91		RAB35_HUMAN (1-201): 1.97e-87: 257: 36.72