HitPredict

Interactor 1: EPHA2 (P29317)
Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)
Gene: EPHA2

Interactor 2: AFAD (P55196)
Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6) (Afadin adherens junction formation factor)
Gene: AFDN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 34079125
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PDZ~fn3, PDZ~SAM_1
Common GO terms GO:0005886 - plasma membrane
GO:0007155 - cell adhesion
GO:0045296 - cadherin binding
GO:0070160 - tight junction
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 976
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024