Interactor 1: EPHA2 (P29317)
Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)
Gene: EPHA2
Interactor 2: EPHA7 (Q15375)
Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) (EHK-3) (EPH-like kinase 11) (EK11) (hEK11)
Gene: EPHA7
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.77 | 1.00 | 0.883 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 33961781, 35384245, 22036564 |
| Identification Methods | affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, comigration in sds page |
| Interaction Type | physical association, association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | EphA2_TM~PK_Tyr_Ser-Thr, Ephrin_lbd~Ephrin_lbd, Ephrin_lbd~fn3, fn3~fn3, PK_Tyr_Ser-Thr~fn3, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~SAM_1, SAM_1~SAM_1 |
| Common GO terms | GO:0005005 - transmembrane-ephrin receptor activity GO:0005524 - ATP binding GO:0005886 - plasma membrane GO:0007411 - axon guidance GO:0016310 - phosphorylation and 4 others more... |
| Homologous interactions | 19 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
