HitPredict

Interactor 1: EPHA2 (P29317)
Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)
Gene: EPHA2

Interactor 2: RHOH (Q15669)
Rho-related GTP-binding protein RhoH (GTP-binding protein TTF) (Translocation three four protein)
Gene: RHOH

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~fn3
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 976 Hs			1 191
+	Hs
		1072503 EPHA7_HUMAN (4-974): 0: 1128: 50.30		RHOH_HUMAN (1-191): 2.74e-95: 276: 100.00
+	Hs
		436169 EPHA2_HUMAN (1-976): 0: 1141: 100.00		RHOC_HUMAN (6-185): 6.48e-85: 250: 42.25
+	Hs
		665198 EPHA2_HUMAN (1-976): 0: 1141: 100.00		RHOB_HUMAN (6-191): 6.57e-85: 250: 40.93
+	Hs
		436317 EPHA7_HUMAN (4-974): 0: 1128: 50.30		RHOC_HUMAN (6-185): 6.48e-85: 250: 42.25
+	Hs
		915694 EPHA7_HUMAN (4-974): 0: 1128: 50.30		RHOB_HUMAN (6-191): 6.57e-85: 250: 40.93
+	Hs
		436223 EPHA5_HUMAN (11-976): 0: 1127: 51.34		RHOC_HUMAN (6-185): 6.48e-85: 250: 42.25
+	Hs
		665201 EPHA2_HUMAN (1-976): 0: 1141: 100.00		RAC1_HUMAN (2-191): 2.63e-75: 226: 39.09
+	Hs
		564420 EPHA2_HUMAN (1-976): 0: 1141: 100.00		RHOQ_HUMAN (5-190): 8.15e-74: 222: 39.49
+	Hs
		665192 EPHA2_HUMAN (1-976): 0: 1141: 100.00		CDC42_HUMAN (2-181): 1.52e-73: 221: 42.25
+	Hs
		545218 EPHA2_HUMAN (1-976): 0: 1141: 100.00		RAC2_HUMAN (2-191): 1.96e-72: 218: 38.07
+	Hs
		665191 EPHA2_HUMAN (1-976): 0: 1141: 100.00		RAC3_HUMAN (2-171): 3.86e-72: 218: 41.81
+	Hs
		665208 EPHA2_HUMAN (1-976): 0: 1141: 100.00		RHOG_HUMAN (2-191): 2.32e-71: 216: 37.56
+	Hs
		665194 EPHA2_HUMAN (1-976): 0: 1141: 100.00		RHOA_HUMAN (6-191): 8.9e-71: 214: 39.38
+	Hs
		925297 EPHA7_HUMAN (4-974): 0: 1128: 50.30		RAC1_HUMAN (2-191): 2.63e-75: 226: 39.09
+	Hs
		564541 EPHA7_HUMAN (4-974): 0: 1128: 50.30		RHOQ_HUMAN (5-190): 8.15e-74: 222: 39.49
+	Hs
		545394 EPHA7_HUMAN (4-974): 0: 1128: 50.30		RAC2_HUMAN (2-191): 1.96e-72: 218: 38.07
+	Hs
		892388 EPHA7_HUMAN (4-974): 0: 1128: 50.30		RAC3_HUMAN (2-171): 3.86e-72: 218: 41.81
+	Hs
		545285 EPHA5_HUMAN (11-976): 0: 1127: 51.34		RAC2_HUMAN (2-191): 1.96e-72: 218: 38.07
+	Hs
		951011 EPHA7_HUMAN (4-974): 0: 1128: 50.30		RHOG_HUMAN (2-191): 2.32e-71: 216: 37.56
+	Hs
		900497 EPHA7_HUMAN (4-974): 0: 1128: 50.30		RHOA_HUMAN (6-191): 8.9e-71: 214: 39.38