HitPredict

Interactor 1: EPHA2 (P29317)
Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)
Gene: EPHA2

Interactor 2: PARD3 (Q8TEW0)
Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha)
Gene: PARD3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~fn3, PDZ~SAM_1
Common GO terms	GO:0005886 - plasma membrane GO:0007155 - cell adhesion GO:0070160 - tight junction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 976 Hs			1 1356
+	Hs
		1072560 EPHA7_HUMAN (4-974): 0: 1128: 50.30		PARD3_HUMAN (1-1356): 0: 709: 100.00
+	Hs
		872464 EPHA5_HUMAN (11-976): 0: 1127: 51.34		PARD3_HUMAN (1-1356): 0: 709: 100.00
+	Hs
		872679 EPHA4_HUMAN (1-976): 0: 1121: 50.25		PARD3_HUMAN (1-1356): 0: 709: 100.00
+	Hs
		665414 EPHA3_HUMAN (24-976): 0: 1111: 51.19		PARD3_HUMAN (1-1356): 0: 709: 100.00
+	Hs
		600627 EPHA1_HUMAN (17-967): 0: 959: 49.38		PARD3_HUMAN (1-1356): 0: 709: 100.00
+	Hs
		872669 EPHA4_HUMAN (1-976): 0: 1121: 50.25		MAGI2_HUMAN (68-1181): 1.8e-38: 159: 13.66
+	Hs
		665228 EPHA2_HUMAN (1-976): 0: 1141: 100.00		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Hs
		1072546 EPHA7_HUMAN (4-974): 0: 1128: 50.30		LNX2_HUMAN (50-361): 6.83e-21: 101: 11.35
+	Hs
		1020163 EPHA7_HUMAN (4-974): 0: 1128: 50.30		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Hs
		872431 EPHA5_HUMAN (11-976): 0: 1127: 51.34		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Hs
		872638 EPHA4_HUMAN (1-976): 0: 1121: 50.25		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Hs
		1072558 EPHA7_HUMAN (4-974): 0: 1128: 50.30		LNX1_HUMAN (73-395): 1.66e-13: 77.4: 12.79
+	Hs
		665393 EPHA3_HUMAN (24-976): 0: 1111: 51.19		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Hs
		872678 EPHA4_HUMAN (1-976): 0: 1121: 50.25		LNX1_HUMAN (73-395): 1.66e-13: 77.4: 12.79
+	Hs
		1049958 EPHA7_HUMAN (4-974): 0: 1128: 50.30		SCRIB_HUMAN (66-355): 5.59e-09: 63.1: 12.75
+	Hs
		665589 EPHB2_HUMAN (28-973): 0: 1089: 48.29		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Hs
		665633 EPHB2_HUMAN (28-973): 0: 1089: 48.29		LNX1_HUMAN (73-395): 1.66e-13: 77.4: 12.79
+	Hs
		665600 EPHB2_HUMAN (28-973): 0: 1089: 48.29		SCRIB_HUMAN (66-355): 5.59e-09: 63.1: 12.75
+	Hs
		872410 EPHB3_HUMAN (22-971): 0: 1051: 47.43		LNX1_HUMAN (73-395): 1.66e-13: 77.4: 12.79
+	Hs
		600564 EPHA1_HUMAN (17-967): 0: 959: 49.38		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50