HitPredict

Interactor 1: EPHA2 (P29317)
Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)
Gene: EPHA2

Interactor 2: E41LA (Q9HCS5)
Band 4.1-like protein 4A (Erythrocyte membrane protein band 4.1-like 4A) (Protein NBL4)
Gene: EPB41L4A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FERM_M~PK_Tyr_Ser-Thr
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 976 Hs			1 686
+	Hs
		546943 EPHA2_HUMAN (1-976): 0: 1141: 100.00		EZRI_HUMAN (7-552): 1.97e-116: 363: 18.94
+	Hs
		665158 EPHA2_HUMAN (1-976): 0: 1141: 100.00		MERL_HUMAN (6-570): 1.28e-111: 350: 20.10
+	Hs
		640048 EPHB2_HUMAN (28-973): 0: 1089: 48.29		MOES_HUMAN (7-555): 4.9e-113: 353: 18.00
+	Hs
		665554 EPHB2_HUMAN (28-973): 0: 1089: 48.29		MERL_HUMAN (6-570): 1.28e-111: 350: 20.10
+	Hs
		674528 UFO_HUMAN (294-911): 1.98e-146: 459: 24.49		E41L1_HUMAN (9-665): 9.7e-142: 437: 25.48
+	Hs
		505564 UFO_HUMAN (294-911): 1.98e-146: 459: 24.49		EPB41_HUMAN (9-675): 1.72e-126: 397: 24.78
+	Hs
		674532 UFO_HUMAN (294-911): 1.98e-146: 459: 24.49		E41L5_HUMAN (8-414): 2.29e-126: 393: 37.23
+	Hs
		204618 UFO_HUMAN (294-911): 1.98e-146: 459: 24.49		E41L2_HUMAN (8-635): 1.98e-121: 387: 23.56
+	Hs
		505551 FGFR3_HUMAN (381-889): 9.01e-137: 431: 24.65		EPB41_HUMAN (9-675): 1.72e-126: 397: 24.78
+	Hs
		299238 FGFR3_HUMAN (381-889): 9.01e-137: 431: 24.65		FARP2_HUMAN (8-560): 2.16e-123: 394: 24.96
+	Hs
		411302 INSR_HUMAN (281-933): 1.71e-136: 445: 24.85		PTN3_HUMAN (10-575): 1.91e-113: 364: 23.92
+	Hs
		435541 IGF1R_HUMAN (393-877): 8.17e-134: 437: 30.00		MOES_HUMAN (7-555): 4.9e-113: 353: 18.00
+	Hs
		435559 IGF1R_HUMAN (393-877): 8.17e-134: 437: 30.00		MERL_HUMAN (6-570): 1.28e-111: 350: 20.10
+	Hs
		434008 LYN_HUMAN (607-879): 2.06e-64: 228: 42.91		E41L1_HUMAN (9-665): 9.7e-142: 437: 25.48
+	Hs
		434004 LYN_HUMAN (607-879): 2.06e-64: 228: 42.91		E41LB_HUMAN (6-610): 3.3e-131: 410: 26.85
+	Hs
		433541 LYN_HUMAN (607-879): 2.06e-64: 228: 42.91		EPB41_HUMAN (9-675): 1.72e-126: 397: 24.78
+	Hs
		299230 LYN_HUMAN (607-879): 2.06e-64: 228: 42.91		FARP2_HUMAN (8-560): 2.16e-123: 394: 24.96
+	Hs
		433778 LYN_HUMAN (607-879): 2.06e-64: 228: 42.91		PTN14_HUMAN (11-686): 3.19e-120: 388: 19.83
+	Hs
		204599 LYN_HUMAN (607-879): 2.06e-64: 228: 42.91		E41L2_HUMAN (8-635): 1.98e-121: 387: 23.56
+	Hs
		433617 LYN_HUMAN (607-879): 2.06e-64: 228: 42.91		MERL_HUMAN (6-570): 1.28e-111: 350: 20.10