HitPredict

Interactor 1: EPHA2 (P29317)
Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)
Gene: EPHA2

Interactor 2: SRPRB (Q9Y5M8)
Signal recognition particle receptor subunit beta (SR-beta) (Protein APMCF1)
Gene: SRPRB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 976 Hs			1 271
+	Hs
		665207 EPHA2_HUMAN (1-976): 0: 1141: 100.00		ARF5_HUMAN (46-240): 5.42e-75: 227: 21.03
+	Hs
		665196 EPHA2_HUMAN (1-976): 0: 1141: 100.00		ARF6_HUMAN (60-239): 5.9e-70: 215: 20.00
+	Hs
		912916 EPHA7_HUMAN (4-974): 0: 1128: 50.30		ARF6_HUMAN (60-239): 5.9e-70: 215: 20.00
+	Hs
		665691 EPHB2_HUMAN (28-973): 0: 1089: 48.29		SRPRB_HUMAN (1-271): 4.47e-69: 216: 100.00
+	Hs
		665572 EPHB2_HUMAN (28-973): 0: 1089: 48.29		ARF6_HUMAN (60-239): 5.9e-70: 215: 20.00
+	Hs
		574601 EPHA8_HUMAN (28-975): 0: 1049: 46.72		ARF4_HUMAN (46-240): 2.72e-63: 198: 20.51
+	Hs
		665188 EPHA2_HUMAN (1-976): 0: 1141: 100.00		ARL4C_HUMAN (67-197): 1.37e-11: 64: 25.56
+	Hs
		872604 EPHB4_HUMAN (14-970): 0: 986: 44.99		SRPRB_HUMAN (1-271): 4.47e-69: 216: 100.00
+	Hs
		872520 EPHB4_HUMAN (14-970): 0: 986: 44.99		ARF6_HUMAN (60-239): 5.9e-70: 215: 20.00
+	Hs
		171285 EPHB6_HUMAN (28-962): 0: 871: 37.66		ARF4_HUMAN (46-240): 2.72e-63: 198: 20.51
+	Hs
		537782 INSRR_HUMAN (287-911): 2.3e-146: 470: 27.55		SRPRB_HUMAN (1-271): 4.47e-69: 216: 100.00
+	Hs
		1018380 MERTK_HUMAN (270-900): 9.58e-146: 460: 23.90		SRPRB_HUMAN (1-271): 4.47e-69: 216: 100.00
+	Hs
		674579 UFO_HUMAN (294-911): 1.98e-146: 459: 24.49		SRPRB_HUMAN (1-271): 4.47e-69: 216: 100.00
+	Hs
		674380 UFO_HUMAN (294-911): 1.98e-146: 459: 24.49		ARF6_HUMAN (60-239): 5.9e-70: 215: 20.00
+	Hs
		537716 INSRR_HUMAN (287-911): 2.3e-146: 470: 27.55		ARF4_HUMAN (46-240): 2.72e-63: 198: 20.51
+	Hs
		411537 INSR_HUMAN (281-933): 1.71e-136: 445: 24.85		SRPRB_HUMAN (1-271): 4.47e-69: 216: 100.00
+	Hs
		411349 INSR_HUMAN (281-933): 1.71e-136: 445: 24.85		ARF6_HUMAN (60-239): 5.9e-70: 215: 20.00
+	Hs
		574602 UFO_HUMAN (294-911): 1.98e-146: 459: 24.49		ARF4_HUMAN (46-240): 2.72e-63: 198: 20.51
+	Hs
		435530 IGF1R_HUMAN (393-877): 8.17e-134: 437: 30.00		ARF4_HUMAN (46-240): 2.72e-63: 198: 20.51
+	Hs
		674537 UFO_HUMAN (294-911): 1.98e-146: 459: 24.49		SAR1A_HUMAN (62-195): 1.47e-11: 64: 24.63