HitPredict

Interactor 1: EPHA3 (P29320)
Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) (hEK4) (HEK) (Human embryo kinase) (Tyrosine-protein kinase TYRO4) (Tyrosine-protein kinase receptor ETK1) (Eph-like tyrosine kinase 1)
Gene: EPHA3

Interactor 2: SLAF1 (Q13291)
Signaling lymphocytic activation molecule (CDw150) (IPO-3) (SLAM family member 1) (CD antigen CD150)
Gene: SLAMF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007155 - cell adhesion
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 983 Hs			1 335
+	Hs
		665402 EPHA3_HUMAN (1-983): 0: 1248: 100.00		CEA21_HUMAN (7-295): 5.06e-49: 167: 17.51
+	Hs
		507926 EPHA4_HUMAN (8-983): 0: 1164: 62.40		FGFR1_HUMAN (20-333): 4.68e-46: 168: 9.12
+	Hs
		872657 EPHA4_HUMAN (8-983): 0: 1164: 62.40		CEA21_HUMAN (7-295): 5.06e-49: 167: 17.51
+	Hs
		601484 EPHA4_HUMAN (8-983): 0: 1164: 62.40		FGFR2_HUMAN (24-327): 1.1e-23: 103: 10.29
+	Hs
		665204 EPHA2_HUMAN (27-983): 0: 1061: 50.47		CXAR_HUMAN (10-334): 1.04e-51: 176: 13.68
+	Hs
		507871 EPHA2_HUMAN (27-983): 0: 1061: 50.47		FGFR1_HUMAN (20-333): 4.68e-46: 168: 9.12
+	Hs
		601465 EPHA2_HUMAN (27-983): 0: 1061: 50.47		FGFR2_HUMAN (24-327): 1.1e-23: 103: 10.29
+	Hs
		665239 EPHA2_HUMAN (27-983): 0: 1061: 50.47		OPCM_HUMAN (19-258): 6.48e-24: 102: 10.08
+	Hs
		685227 EPHB4_HUMAN (17-977): 0: 1027: 47.44		CEAM8_HUMAN (45-251): 6.59e-22: 96.5: 16.51
+	Hs
		600584 EPHA1_HUMAN (7-973): 0: 949: 42.52		CEA21_HUMAN (7-295): 5.06e-49: 167: 17.51
+	Hs
		435630 IGF1R_HUMAN (366-883): 1.6e-139: 453: 30.02		SLAF1_HUMAN (1-335): 3.45e-80: 249: 100.00
+	Hs
		435514 IGF1R_HUMAN (366-883): 1.6e-139: 453: 30.02		FGFR1_HUMAN (20-333): 4.68e-46: 168: 9.12
+	Hs
		435501 IGF1R_HUMAN (366-883): 1.6e-139: 453: 30.02		CD48_HUMAN (35-256): 1.1e-43: 152: 23.66
+	Hs
		412176 FYN_HUMAN (615-879): 1.08e-64: 229: 44.20		SLAF1_HUMAN (1-335): 3.45e-80: 249: 100.00
+	Mm
		763408 FYN_MOUSE (615-879): 3.46e-64: 228: 43.82		SLAF1_MOUSE (1-335): 1.89e-69: 222: 59.77
+	Hs
		412347 FYN_HUMAN (615-879): 1.08e-64: 229: 44.20		CD244_HUMAN (23-331): 5e-50: 172: 19.12
+	Hs
		411939 FYN_HUMAN (615-879): 1.08e-64: 229: 44.20		CD2_HUMAN (14-323): 1.49e-47: 165: 18.79
+	Hs
		412008 FYN_HUMAN (615-879): 1.08e-64: 229: 44.20		FGFR2_HUMAN (24-327): 1.1e-23: 103: 10.29