HitPredict

Interactor 1: EPHA3 (P29320)
Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) (hEK4) (HEK) (Human embryo kinase) (Tyrosine-protein kinase TYRO4) (Tyrosine-protein kinase receptor ETK1) (Eph-like tyrosine kinase 1)
Gene: EPHA3

Interactor 2: CAC1C (Q13936)
Voltage-dependent L-type calcium channel subunit alpha-1C (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Voltage-gated calcium channel subunit alpha Cav1.2)
Gene: CACNA1C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	37207277
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030425 - dendrite
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 983 Hs			1 2221
+	Hs
		872439 EPHA5_HUMAN (7-983): 0: 1202: 65.97		CAC1C_HUMAN (1-2221): 0: 1887: 100.00
+	Hs
		1047091 EPHA7_HUMAN (6-979): 0: 1198: 61.46		CAC1C_HUMAN (1-2221): 0: 1887: 100.00
+	Hs
		665598 EPHB2_HUMAN (29-981): 0: 1167: 55.90		CAC1C_HUMAN (1-2221): 0: 1887: 100.00
+	Hs
		872644 EPHA4_HUMAN (8-983): 0: 1164: 62.40		CAC1C_HUMAN (1-2221): 0: 1887: 100.00
+	Hs
		872613 EPHB1_HUMAN (28-983): 0: 1162: 55.69		CAC1C_HUMAN (1-2221): 0: 1887: 100.00
+	Hs
		1047303 EPHA6_HUMAN (3-980): 0: 1146: 60.16		CAC1C_HUMAN (1-2221): 0: 1887: 100.00
+	Hs
		665475 EPHA8_HUMAN (29-982): 0: 1099: 56.57		CAC1C_HUMAN (1-2221): 0: 1887: 100.00
+	Hs
		412186 FYN_HUMAN (615-879): 1.08e-64: 229: 44.20		CAC1C_HUMAN (1-2221): 0: 1887: 100.00
+	Hs
		872476 EPHA5_HUMAN (7-983): 0: 1202: 65.97		SCN2A_HUMAN (1221-1548): 8.66e-16: 86.5: 16.45
+	Hs
		242616 FYN_HUMAN (615-879): 1.08e-64: 229: 44.20		CAC1F_HUMAN (1860-2191): 6.18e-21: 103: 24.14