HitPredict

Interactor 1: EPHA3 (P29320)
Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) (hEK4) (HEK) (Human embryo kinase) (Tyrosine-protein kinase TYRO4) (Tyrosine-protein kinase receptor ETK1) (Eph-like tyrosine kinase 1)
Gene: EPHA3

Interactor 2: LRC49 (Q8IUZ0)
Leucine-rich repeat-containing protein 49 (Centriolar satellite-associated tubulin polyglutamylase complex regulator 2) (Tubulin polyglutamylase complex subunit 4) (PGs4)
Gene: LRRC49

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	LRR_4~PK_Tyr_Ser-Thr
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 983 Hs			1 686
+	Hs
		665495 EPHA8_HUMAN (29-982): 0: 1099: 56.57		LRC49_HUMAN (1-686): 1.23e-102: 330: 100.00
+	Hs
		665420 EPHA3_HUMAN (1-983): 0: 1248: 100.00		ERBIN_HUMAN (71-443): 9.62e-37: 150: 19.61
+	Hs
		872473 EPHA5_HUMAN (7-983): 0: 1202: 65.97		ERBIN_HUMAN (71-443): 9.62e-37: 150: 19.61
+	Hs
		1072577 EPHA7_HUMAN (6-979): 0: 1198: 61.46		ERBIN_HUMAN (71-443): 9.62e-37: 150: 19.61
+	Hs
		1049958 EPHA7_HUMAN (6-979): 0: 1198: 61.46		SCRIB_HUMAN (4-255): 3.48e-34: 142: 18.51
+	Hs
		665440 EPHA3_HUMAN (1-983): 0: 1248: 100.00		NISCH_HUMAN (95-193): 9.95e-11: 67.4: 26.21
+	Hs
		665419 EPHA3_HUMAN (1-983): 0: 1248: 100.00		LRIQ1_HUMAN (119-237): 1.92e-10: 66.6: 26.89
+	Hs
		872694 EPHA4_HUMAN (8-983): 0: 1164: 62.40		ERBIN_HUMAN (71-443): 9.62e-37: 150: 19.61
+	Hs
		665600 EPHB2_HUMAN (29-981): 0: 1167: 55.90		SCRIB_HUMAN (4-255): 3.48e-34: 142: 18.51
+	Hs
		872509 EPHA5_HUMAN (7-983): 0: 1202: 65.97		NISCH_HUMAN (95-193): 9.95e-11: 67.4: 26.21
+	Hs
		1072633 EPHA7_HUMAN (6-979): 0: 1198: 61.46		NISCH_HUMAN (95-193): 9.95e-11: 67.4: 26.21
+	Hs
		1072575 EPHA7_HUMAN (6-979): 0: 1198: 61.46		LRIQ1_HUMAN (119-237): 1.92e-10: 66.6: 26.89
+	Hs
		232788 EPHA2_HUMAN (27-983): 0: 1061: 50.47		PHLP1_HUMAN (2-482): 2.72e-46: 179: 11.34
+	Hs
		665686 EPHB2_HUMAN (29-981): 0: 1167: 55.90		NISCH_HUMAN (95-193): 9.95e-11: 67.4: 26.21
+	Hs
		665646 EPHB2_HUMAN (29-981): 0: 1167: 55.90		LRIQ1_HUMAN (119-237): 1.92e-10: 66.6: 26.89
+	Hs
		872733 EPHA4_HUMAN (8-983): 0: 1164: 62.40		NISCH_HUMAN (95-193): 9.95e-11: 67.4: 26.21
+	Hs
		665318 EPHA2_HUMAN (27-983): 0: 1061: 50.47		ERBIN_HUMAN (71-443): 9.62e-37: 150: 19.61
+	Hs
		665544 EPHA8_HUMAN (29-982): 0: 1099: 56.57		NISCH_HUMAN (95-193): 9.95e-11: 67.4: 26.21
+	Hs
		665370 EPHA2_HUMAN (27-983): 0: 1061: 50.47		NISCH_HUMAN (95-193): 9.95e-11: 67.4: 26.21
+	Hs
		665312 EPHA2_HUMAN (27-983): 0: 1061: 50.47		LRIQ1_HUMAN (119-237): 1.92e-10: 66.6: 26.89